I have been taking mycophenolate sodium (very similar to MMF) for nearly 6 weeks now and am at the full dose of 360 mg bd, currently tolerating the dose fine, but have had a lot of (seemingly random) fluctuations in my kidney function ranging from normal values of more than 90ml/min eGFR to 56 ml/min over the past few months. I am also currently on 20mg pred daily and had my first Rituximab treatment in mid october 2014 which has at the moment not had any or much perceivable effect. I was wondering if anyone else who has or is suffering from SLE has had similar treatment and issues with their kidneys and what sort of results they got from various treatments? Is it normal for eGFR values to fluctuate whilst in the early stages of taking Mycophenolate sodium or MMF ? How long does it take for kidney function to stabilise if ever with Mycophenolate? I am nearly 22 now this has been my only flare since my first flare at diagnosis at 17 in 2010 my initial treatment involved IV pred and then a combination of MMF and oral pred which helped the lupus nephritis very quickly. Treatment has not proved so effective with this flare and so was wondering about other peoples experiences?