Hi, Mags here. Well, after 20 months of combination Pemetrexed and Pemulizimab my latest scan shows some further growth in the lymph nodes, although the primary tumour in the lung is fairly static. My oncologist has decided that as the current treatment - i.e. neither the immuno or chemo therapies, are working now they are being discontinued. However, and this may be of interest to many of you, he said that since my initial diagnosis and testing for mutations (which were done on the over 1 litre of fluid taken from my pleura) there have been other mutations uncovered and he wants to test me for those. There are 2 issues for me; 1. the tumours are in a difficult place to take a biopsy and no further fluid has built up to take samples from and 2. it is still a long shot that any of the mutations will be present that can be treated by tablet chemo. So, I am to have a PET scan to determine the exact position on the tumours and if they can be safely accessed for biopsy and if so then a bronchoscopy with ultrasound and a biopsy for screening for any of the newly discovered mutations will be carried out. This has been scheduled for next Thursday, although I haven't yet had an appointment for the PET scan - this will need to be soon as I have to have a COVID test Monday and then self isolate until the bronchoscopy. My lung nurse has also told me that if i am not able to have the biopsy, there is a blood test that needs to be sent to the US and there is some wiggle room for this to be done on the NHS, although I am willing to pay if not. So the treatments etc move on, do they not?!
If the mutations are not there then my next line of treatment is to have a further course of a more brutal chemo with loss of my hair - which is short anyway! Not keen on this as I haven't exactly enjoyed the side effects of the previous chemo - but - hey ho.
I thought I'd post this so that other people can ask their team about these new developments.
Anyone got any advice re the bronchoscopy??
Be careful out there. Mags x