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Pemetrexed
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Good news from the ATTLAS trial for patients with EGFR mutations and ALK translocations.
Treatment with atezolizumab, bevacizumab, paclitaxel, and carboplatin (ABCP) was significantly more effective than
pemetrexed
plus carboplatin or cisplatin https://dailynews.ascopubs.org/do/atezolizumab-bevacizumab-and-chemotherapy-improves-pfs-egfr---alk--mutated-nsclc-after?
Treatment with atezolizumab, bevacizumab, paclitaxel, and carboplatin (ABCP) was significantly more effective than
pemetrexed
plus carboplatin or cisplatin https://dailynews.ascopubs.org/do/atezolizumab-bevacizumab-and-chemotherapy-improves-pfs-egfr---alk--mutated-nsclc-after?
Denzie
Volunteer
in
Lung Cancer Support
6 months ago
Stage 4 lung cancer - treatment
His treatment plan was to have Cisplatin and
Pemetrexed
(chemotherapy) and Pembrolizumab (Immunotherapy). He tolerated a number of cycles but then got a couple of infections at once and was very poorly.
His treatment plan was to have Cisplatin and
Pemetrexed
(chemotherapy) and Pembrolizumab (Immunotherapy). He tolerated a number of cycles but then got a couple of infections at once and was very poorly.
Clark74517796
in
The Roy Castle Lung Cancer Foundation
18 days ago
Blip in Immunitherapy ?
My husband has stage 4 non small cell lung cancer He was diagnosed about 10 months ago and has been responding well to immunotherapy and chemotherapy (3 weekly treatments of
pemetrexed
and pembrolizubmab spelling maybe a bit wrong?)
My husband has stage 4 non small cell lung cancer He was diagnosed about 10 months ago and has been responding well to immunotherapy and chemotherapy (3 weekly treatments of
pemetrexed
and pembrolizubmab spelling maybe a bit wrong?)
Holepunch
in
The Roy Castle Lung Cancer Foundation
11 months ago
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Bad Chemo Reaction?
I was diagnosed in Sept last year with stage 4 NSCLC and put on treatment plan of Chemo (
Pemetrexed
and Carboplatin) plus Immunotherapy.
I was diagnosed in Sept last year with stage 4 NSCLC and put on treatment plan of Chemo (
Pemetrexed
and Carboplatin) plus Immunotherapy.
Subi123
in
The Roy Castle Lung Cancer Foundation
1 year ago
Starting Tagrisso
After four rounds of Keytruda,
Pemetrexed
, and Carboplatin a PET scan showed primary tumor had increased in size. My doctor then ordered a biopsy which tested positive for EGFR mutation. I had a three week course of radiation and just started Tagrisso two days ago. All my joints are sore.
After four rounds of Keytruda,
Pemetrexed
, and Carboplatin a PET scan showed primary tumor had increased in size. My doctor then ordered a biopsy which tested positive for EGFR mutation. I had a three week course of radiation and just started Tagrisso two days ago. All my joints are sore.
HeidiEg
in
Lung Cancer Support
1 year ago
B12 & Folate Deficiency and tolerability of antibiotics (why I react badly to them)
For example: "A total of 12 patients had folate deficiency, and 10 of those suffered from severe toxicity (grade 3 or more)" "
Pemetrexed
(Alimta®) is a novel multi-target antifolate that inhibits several enzymes involved in DNA synthesis such as thymidylate synthase (TS), dihydrofolate reductase (DHFR
For example: "A total of 12 patients had folate deficiency, and 10 of those suffered from severe toxicity (grade 3 or more)" "
Pemetrexed
(Alimta®) is a novel multi-target antifolate that inhibits several enzymes involved in DNA synthesis such as thymidylate synthase (TS), dihydrofolate reductase (DHFR
Whoa182
in
Pernicious Anaemia Society
1 year ago
Setback
I had 4 sessions, the first with
pemetrexed
and carboplatin. but the following three I only got carboplatin, due to my kidneys giving a GFR reading of 37. The last chemo was 25 Nov and then I had a contrast CT scan on the 28th.
I had 4 sessions, the first with
pemetrexed
and carboplatin. but the following three I only got carboplatin, due to my kidneys giving a GFR reading of 37. The last chemo was 25 Nov and then I had a contrast CT scan on the 28th.
ginkgo
in
The Roy Castle Lung Cancer Foundation
1 year ago
Any input/advice please on radiotherapy post immunotherapy?
I started off with
pemetrexed
, carboplatin and pembrolizumab, then moved to maintenance
pemetrexed
and pembrolizumab, then pembrolizumab only at six weekly intervals during Covid. I’ve been on it ever since (private health insurance). It’s worked really well.
I started off with
pemetrexed
, carboplatin and pembrolizumab, then moved to maintenance
pemetrexed
and pembrolizumab, then pembrolizumab only at six weekly intervals during Covid. I’ve been on it ever since (private health insurance). It’s worked really well.
Ellejayb
in
The Roy Castle Lung Cancer Foundation
1 year ago
Should I ask for a new assessment - fourth edition
I start on carboplatin and
pemetrexed
and hope I get another lucky break and it works. If it all goes to pot, at least I enjoyed the summer, thanks to the unusually successful sessions of palliative radiotherapy and will always be grateful for this unexpected bonus.
I start on carboplatin and
pemetrexed
and hope I get another lucky break and it works. If it all goes to pot, at least I enjoyed the summer, thanks to the unusually successful sessions of palliative radiotherapy and will always be grateful for this unexpected bonus.
ginkgo
in
The Roy Castle Lung Cancer Foundation
2 years ago
Hello there - any advice about Chemo (Carboplatin and Pemetrexed) and Immunotherapy (Pembrolizomab)?
Hi, so I was diagnosed just before Christmas (Is cancer the Christmas Grinch? 🤔 It was in my case....) Anyway, having been diagnosed with NSCL cancer I've now been put on a treatment plan, and start on Monday next week. Has anyone got any top tips for getting through the next few months? It all sounds
Hi, so I was diagnosed just before Christmas (Is cancer the Christmas Grinch? 🤔 It was in my case....) Anyway, having been diagnosed with NSCL cancer I've now been put on a treatment plan, and start on Monday next week. Has anyone got any top tips for getting through the next few months? It all sounds
Boo_Radley
in
The Roy Castle Lung Cancer Foundation
1 year ago
My brother
He's having
Pemetrexed
and Carboplatin - he's having Pembrolizumab at the same time - finding it very difficult to stay positive at the moment but I never let him see - he suffers from anxiety & depression unfortunately - tough times - Thank you - grateful for any info received x
He's having
Pemetrexed
and Carboplatin - he's having Pembrolizumab at the same time - finding it very difficult to stay positive at the moment but I never let him see - he suffers from anxiety & depression unfortunately - tough times - Thank you - grateful for any info received x
Brianderrick12
in
The Roy Castle Lung Cancer Foundation
2 years ago
chemo & immunotherapy
I am starting chemo and immunotherapy (carboplatin-
pemetrexed
-pembrolizumab) on Tuesday. I had my right lung removed 2020 had a reaccurance on the lining right area January this year and had radiotherapy but unfortunately I have another reaccurance. Any info would be much appreciated 😘
I am starting chemo and immunotherapy (carboplatin-
pemetrexed
-pembrolizumab) on Tuesday. I had my right lung removed 2020 had a reaccurance on the lining right area January this year and had radiotherapy but unfortunately I have another reaccurance. Any info would be much appreciated 😘
Eglingham
in
The Roy Castle Lung Cancer Foundation
2 years ago
Pemetrexed maintenance/ Pneumonitis
Well the maintenance started well. Got first week in then second week got what I thought was side effects. I ticked them all but by middle of week felt more like a chest infection. Got in touch with the hot line number as temperature was spiking at 38.8. Went in for check up into Poole Hospital and
Well the maintenance started well. Got first week in then second week got what I thought was side effects. I ticked them all but by middle of week felt more like a chest infection. Got in touch with the hot line number as temperature was spiking at 38.8. Went in for check up into Poole Hospital and
Ollie13
in
The Roy Castle Lung Cancer Foundation
2 years ago
New and scared
I’ve just been diagnosed with Metastatic adenocarcinoma of the lung and am starting palliative treatment of Carboplatin/
Pemetrexed
/Pembrolizumab therapy on Tuesday. This all has come completely out of the blue to me, and I understand very little of what I might expect.
I’ve just been diagnosed with Metastatic adenocarcinoma of the lung and am starting palliative treatment of Carboplatin/
Pemetrexed
/Pembrolizumab therapy on Tuesday. This all has come completely out of the blue to me, and I understand very little of what I might expect.
Damonaldinho
in
The Roy Castle Lung Cancer Foundation
2 years ago
Treatment has stoped working - next steps
Well, after 20 months of combination
Pemetrexed
and Pemulizimab my latest scan shows some further growth in the lymph nodes, although the primary tumour in the lung is fairly static.
Well, after 20 months of combination
Pemetrexed
and Pemulizimab my latest scan shows some further growth in the lymph nodes, although the primary tumour in the lung is fairly static.
magstherunner
in
The Roy Castle Lung Cancer Foundation
2 years ago
Chemotherapy Maintenance
I have now just started chemotherapy maintenance with
Pemetrexed
. Hopefully the side effects won't be as bad as the combination I've just finished. Still on the Prednisolone for the inflammation of my right lung due to Radiotherapy side effects.
I have now just started chemotherapy maintenance with
Pemetrexed
. Hopefully the side effects won't be as bad as the combination I've just finished. Still on the Prednisolone for the inflammation of my right lung due to Radiotherapy side effects.
Ollie13
in
The Roy Castle Lung Cancer Foundation
2 years ago
Inflammation update
Spoke to oncologist same day of x-ray and he's putting me on maintenance
Pemetrexed
starting in a couple of weeks. Will be commencing on Folic acid and B12 injection also.
Spoke to oncologist same day of x-ray and he's putting me on maintenance
Pemetrexed
starting in a couple of weeks. Will be commencing on Folic acid and B12 injection also.
Ollie13
in
The Roy Castle Lung Cancer Foundation
2 years ago
Scan following my self imposed "holiday" from Chemo
After missing 3 rounds of
Pemetrexed
chemo (but still receiving pemulizimab immuno) my lung tumour is static but one of the affected lymph nodes in my chest (the only other involvement) has grown - so I've been advised to go back onto the chemo.
After missing 3 rounds of
Pemetrexed
chemo (but still receiving pemulizimab immuno) my lung tumour is static but one of the affected lymph nodes in my chest (the only other involvement) has grown - so I've been advised to go back onto the chemo.
magstherunner
in
The Roy Castle Lung Cancer Foundation
3 years ago
A large injection of hope required. Please.
Eventually I am going to be started on Carboplatin and
Pemetrexed
and I badly need to lift my chin off the ground and regain some fighting spirit. Thank you for being here. Please help me. I do hope that life is good for you and there are some positive responses out there.
Eventually I am going to be started on Carboplatin and
Pemetrexed
and I badly need to lift my chin off the ground and regain some fighting spirit. Thank you for being here. Please help me. I do hope that life is good for you and there are some positive responses out there.
sally70
in
Lung Cancer Support
3 years ago
Chemotherapy Started
Well thought I would let you know I started
Pemetrexed
and Carboplatin on 5th 1st cycle. The staff at the Jigsaw RBH were very supportive and explained everything about my chemotherapy treatment.
Well thought I would let you know I started
Pemetrexed
and Carboplatin on 5th 1st cycle. The staff at the Jigsaw RBH were very supportive and explained everything about my chemotherapy treatment.
Ollie13
in
The Roy Castle Lung Cancer Foundation
3 years ago
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