Sticky Blood-Hughes Syndrome Support
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blood test question

I just dug back through my blood tests, and found the ones that were negative, they were the cardiolipin IgG and IgM the lupus antio coagulant was not repeated at that time. what does it mean if you are positive lupus anticoagulant, but negative cardiolipin antibodies?

I have a form to get bloods done here with anti-cardiolipin antibodies and lupus anticoagulant, is that enough to get a definite answer? Or should I ask for something else?

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Beta2 glycoprotein is the other test

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Hi,

What is important is that you take the tests twice with 12 weeks between them.

You can have the diagnose of HS/APS on only one of the three antibodies positive. In your case Lupus Anticoagulant but the others negative.

They usually take all the three tests, even Anti-Beta2Glycoprotein1 at the same time, but as you have taken the other two earlier they obviously want to know if they are positive today. When did you take the other two tests?

As a matter of fact i think you should ask to have anti-Beta2Glycoprotein 1 tested also.

But then you need to take that a second time to know it is actually positive. They do this to reassure that you do not have an infection the first time. Hope that helps.

Best wishes from Kerstin in Stockholm

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they were done just over two years ago

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As others have said it is normal to repeat tests 12 weeks apart when one of them is positive. You need to ask for anti-Beta2 Glycoprotein1 (antiB2GP1) to be added to the test too.

You can be positive to anyone of those tests or just one of them, it does not matter for a diagnosis and even if your LA was negative this time but you were positive with another antibody. The most important thing as well as the blood tests is your symptoms and medical history. These all go together to add up to the diagnosis.

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Hi,

I must ask you please as I am triple-positive and have always been positive on all three every time.

"Can you be diagnosed for HS/APS if only LA is positive the first time and the anti-Beta2Glycoprotein1 positive the second time only? One of each and 12 weeks at least between the tests? I have perhaps misunderstood as I thought that it had to be both of LA, OR both of Beta-2Glycoprotein, not one of each antibody."

It is important so I do not give a false answer but I also know that there are other things important for a diagnose.

Kerstin

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This was for APsnotFab!

Kerstin

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That was my next question

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There are three tests, some get a triple positive, some pass a couple or just one, or remain seronegative for years, I have now regularly passed two of the tests. Your LA being positive means yes signs of the disease are there on paper for you. MaryF

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