Understanding INR?

[CharH]

Hi

I have only recently been diagnosed after having 4 miscarriages, although have now found that most of the symptoms of "depression/anxiety " I have had over the years (migraines, chronic fatigue and joint pain) are actually down to APS... I knew I wasn't depressed just thought maybe I was going a bit nuts and imagining it, lol.

Anyway I see many of you talk about your INR level being important to how you feel, especially in terms of brain function (mine at the moment seems to barely function at all)

My INR in Feb was 1.0 and I have today been put on low dose aspirin to complement the amitriptyline and hydroxychloriquine. I havent had any strokes or DVT but does this seem a low INR? And any info on how long it takes the aspirin to bring it up a little and hopefully lift the 'brain fog'??

Thanks in advance 😊

[Manofmendip]

Hello and welcome.

Aspirin does not affect INR levels at all, it has an anti-platelet action, not an anticoagulation action. You only need to have regular INR tests if you are on Warfarin.

Where are you from and who is managing your APS? This information will help us to help you.

Best wishes.

Dave

[CharH in reply to Manofmendip]

Thanks Dave.

That makes sense as to why the dr didnt seem too worried about my INR. I am on the IOW (UK) and have had 2 appts now with a Rheumatologist.

Hopefully once the Planquil takes effect and the fatigue subsides that'll be enough to sort my head out.

[Manofmendip in reply to CharH]

Thanks for your reply.

Many members on here need to be anticoagulated, with an INR in the region of 3.5 to 4.0 before their symptoms, especially migraines, brain fog and memory problems, become manageable.

Have a look at this link, for APS specialists:

hughes-syndrome.org/self-he...

Dave

[mylafont]

My current INR goal is 3 - 3.5. It was raised a couple months ago from 2.5 - 3. I've also gone from being tested once per month to once every week or two. I was continuing to have new brain lesions appear on my MRIs. Recent MRI has no new ones since increase in both range and test frequency.

[Lure2 in reply to mylafont]

Good to hear!

Kerstin

[Yissica]

An INR of 1 is the figure for anyone not on any form of warfarin anticoagulation. It is a normal baseline for the general public.

Plaquenil works as an antiplatelet but is stronger than aspirin alone.