Faulty batch of Sperm wash solution - help please worried about FET transfer

[Clementine2021]

Hello ladies,

I am a bit worried and would like to speak to anyone else who have received the same message from their clinic as I am really lost and need some help.

I had my eggs removed earlier last month and been informed the sperm wash solution used to create embryos was a faulty batch with low levels of sodium pyruvate.

The clinic has said everything is fine however I have checked on HEFA and Cooper Surgical ( same company who are in the press at the moment for law suits on the faulty freezing solution ) and it says the effects on sperm cells is ‘ unknown’.

I also find it slightly strange that day 4 embryos were all all looking good and suddenly day 6 embryos reduced from 8 embryos all of good quality to 2 blastocyst.

Understand there would be a reduction but this is as way below KPI at 25% for my age.

Am really worried whether to go ahead with my FET transfer in a few weeks encase there is any affect on the embryo and should the cycle work know on to a baby.

I’m waiting to speak to HEFA MD tomorrow for clarity, just don’t know who to believe.

Below was the message from the clinic :

This is to inform you that we have received a notification from Cooper Surgical to ourselves and other clinics on 19-02-2024 about one of their products.

Cooper Surgical are manufacturers of IVF products including a sperm wash solution (media). They wrote to us, and other clinics, to inform us that certain batches of this solution have been found to have lower levels than expected of a supplementary compound, sodium pyruvate. This is not a critical component of this media; all of the critical components such as glucose were normal.

[HollyT7]

I think the drops pretty normal tbh, we went from 8 to 3. From what your clinic have said it doesn’t sound like much impact if any.

[Clementine2021 in reply to HollyT7]

Thank you. X

[raverg]

It’s good that you’re talking to HFEA as probably no one in here will have enough knowledge about the technical part. But on the numbers side, a friend of mine who went into OHSS after the egg collection had 11 embryos on day 3 and then just 3 made it to day 5. I think that it often happens in cases where you produce lots of eggs at once, they tend to be slightly lower quality.

[Clementine2021 in reply to raverg]

Thank you. X

[Twiglet2]

this is quite a normal drop off in my experience too. I’ve no idea what this solution does so good you are talking to the expert but rather way the sperm gas created 2 embryos good enough for freezing so there would be no way I wouldn’t be trying them all n a transfer of it were me 🤗💜 xx

[Hopewhite]

hi lovely I hope you’re well, hopefully you’ve got a response by HFEA now , I’ve just came across with these on the news, the second part of the article talks about CooperSurgical. Hopefully they have identified where the damage is significant and perhaps there’s others where they think it could be limited, hopefully you can get to the bottom of this soon unscathed xx

In our experience of 9 fertilised embryos , only 3 made it to 5 days blastocyst, the other 6 made it to day 6 but were not considered good enough for freezing xx

Wishing you all the best of luck in your journey xx

amp.theguardian.com/uk-news...

[Clementine2021 in reply to Hopewhite]

Thank you and same to you xx

[Here4ivfinfo]

just a quick one. I went from 19 blastocysts on day 3 to 6 by day 6. Just letting you know as it might not be related. I totally get why you’re concerned though!!