hi can anyone explain whats involved with a natural modified fet pls? Dr has suggested to me this as i suffered an allergic reaction to progynova and to my surprise I can’t believe there aint alternative for someone who would have an allergic reaction to progynova😫
The thought of a natural modified is filling me with anxiety. Do you need to have a dominant follicle to reach a certain size before the frozen embryo can be transferred? Is there lots of scans needed? If anyone can shed some light i be grateful x
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keepfaith1982
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I react really badly to progynova and they had to reduce my dose down massively on my first FET (although it was successful) so I was also going with a natural FET to try for a sibling. I can't get my head around the different terminology but there's a fully natural FET where they just transfer after you've ovilated naturally, or they can add progesterone support (that's what I was going with), or I think they can also add a trigger shot so they try to time your ovulation. Clinics seem to differ in how they monitor - some want lots of extra scans and monitoring including blood tests to catch ovulation whereas mine were happy with me using ovulation tests sticks and no extra scans. They just said I needed to have regular ovulation (confirmed by a 21 day progesterone test the month before) and a good lining naturally. Your clinic should give you a detailed overview/protocol of how they do things.
Hello, thanks for explaining. My periods are all over and the place so I don’t understand how this will work for me. Im going to ask about reducing dose. Its really odd as i only experience a tiny rash on zumenon but when on progynova i got a nasty rash and swollen eyes. Natural FET I’m not liking sound off as relying on your body to ovulate seems more harder to control things xx
If it's a private clinic then they're usually pretty flexible and as long as you do ovulate (which if you have periods, is likely) it doesn't matter so much about the cycle length - you'd just start testing from earlier and then call them when you get an LH surge. I found the easiest were the clear blue ones that have a flashing smiley a couple of days before you get the proper surge so you have a little notice. They're not perfect and sometimes mine went from nothing to a solid smiley (i.e., ovulation) but still easier than try to work out what the lines meant. There's not really any control unless the clinic uses a trigger shot, and even then you're still going mainly off your natural cycle. I was really keen on a natural cycle as I hated the progynova (even when I was on one every other day) and there didn't seem to be an alternative, plus my body didn't absorby the synthetic progesterone well and my levels and lining were better naturally. I didn't have an allergic reaction though, just felt terrible and my lining got too thick. Maybe if you're allergic they'll be able to offer something else - there must be other forms of oestrogen out there...
I had a natural modified FET at the start of the year - my clinic asked me to monitor my LH levels, and I had a trigger shot when I ‘peaked’. I had a couple of scans along the way to ensure my lining was good enough, and that my dominant follicle looked as it should.
The transfer was timed for 7 days later, and I started progesterone a few days before the transfer.
They did also check my oestrogen/progesterone levels the day before transfer.
I think as long as you have a regular cycle and a good lining, a natural modified cycle should be just as good (or better!) than a fully modified cycle.
I did become pregnant in this cycle (which unfortunately ended in miscarriage).
I have had several transfers, the 2nd of which was natural. I had 3 scans and then a trigger shot and progesterone support (pessaries).
As my clinic is abroad, I have to pay for scans in the UK, and so have always opted for medicated transfers as my clinic said we had tried natural and so they didn’t have a preference natural or medicated going forward.
I’m now on to transfer 7 (embryos 9 and 10), and after adding steroids, clexane, contraction scan, HCG wash, and embryo glue for transfer 6, my doctor suggested trying natural again.
I explained my only reservations were the cost of multiple scans, and he said they are now willing to use ovulation tests instead of scans. This time from what I’ve read, I understand I’m doing modified natural. Using ovulation strips from day 8 of my next cycle, then an Ovitrelle trigger shot, progesterone support and FET.
I assume he can see from all the previous scans I’ve had prior to transfer that I am ovulating regularly, plus my lining has always been a minimum of just under 8mm even without estrogen support.
It does make me nervous relying on my body to do what it should and ovulate then produce a good lining. But after so many failed transfers I’m willing to fine it a go 🙏🏼
I’ve always liked the control of a medicated cycle, but as Cous said it’s more natural to let your body do it. I’m hoping this makes the difference for me on my next transfer. X
hi there, I only did two ivf rounds before getting pregnant but my first was medicated and didn’t work my second was naturally modified and resulted in my baby being born so it was the best option for me… perhaps or maybe it’s just chance. Either way I much preferred naturally modified. It means tracking your period for ovulation then you trigger the egg to come out then they time the insertion of the egg about a week later.
Hiya, aww congrats on baby 🥰 great it worked for you 🥰 thanks for replying. Its weird that I had a allergic reaction tbh was ok on Zumenon and this cycle they gave progynova and had a nasty rash from It and eyes swelled up. I just don’t like the idea of relying on my body to do half the work xxx
If you have regular periods (and I mean between day 25 and 32) it’s not a bad call. You get extra scans to make sure your lining is growing normally so they won’t implant if it’s not. I found progynova made me feel pregnant when I wasn’t and made me very paranoid so I much preferred this route. I also had acupuncture and took naturally occurring folate (methyl folate) as some bodies can reject the one found in most multi vitamins. You get progesterone to help with the implantation so you’re not entirely alone and you have to track your ovulation so you know when you ovulate so timing works. I was worried about timing but it all worked out and worked out in the end. If I did it again I’d do it the same way.
Thank you! Agree progynova made me feel very emotional. Can I ask what did they reduce progynova down to? Did you need to take it for longer period as dosage reduced?
The way you say the timing of the FET to match your own egg naturally being there makes so much sense! I was also wondering how long after trigger they transfer. Do they trigger you before you naturally ovulate? I’m trying to figure out when my FET could be as it’s looking very close to Easter/half term 🙈
I called the doctor when I got the flashing smiley on the ovulation kit. I had a scan booked the next day so he said to keep that: they scan to make sure your lining is right and then advised me to do the trigger that night (so it’s just making sure if you haven’t ovulated you do now) then take the progesterone a couple of days later about 5 days before the implant.
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