Recommendations on places for a Hysteroscopy

[Natasha2012]

I told myself I wouldn’t test and yet I have been testing since 3dp5dt, now 5dp5dt and negative again . My symptoms have been so severe from the oestrogen and the progesterone . I have been pregnant before and it makes you feel pregnant . I have upmost respect and compassion for women that have multiple cycles . I have a constant Tummy ache and feel nauseous. All I want is a baby with my husband and I’m slowly just feeling like it’s going to be an absolute battle to get there . We ended up having ivf due to his low sperm count ( now sorted due to him going on meds ). But now with my second failed transfer I’m thinking it’s something also to do with me and my c sections I have had . Can anyone who has had prior c sections and then had ivf recommend anyone ? I can’t do another transfer before checking myself.

Lots of love to you all ❤️

[Millbanks]

Hi Natasha,

Sorry to hear you've been struggling - IVF is rough.

I'm sure you're aware but 5dp 5td is early to get a positive - most people seem to get them from 6 / 7 days and some even only on test day.... don't count yourself out yet!

In terms of getting checked, I'm surprised your clinic didn't suggest having one before you started treatment - they usually want to check the womb cavity for lesions / polyps etc. I would speak to your consultant about it.

I wouldn't imagine though that having a c-section previously would hamper your chances of IVF working. I know a lot of people who have had a 2nd baby through IVF (after a first through IVF) and post c-section. But might be good to check for scarring etc anyway.

xx

[Natasha2012 in reply to Millbanks]

I just feel like they wanted my money to be honest . They have said they wouldn’t start investigations until my third failure . I only have one embryo left after this and I can’t go through a third with my only one left . I could take the negative test if I didn’t feel sick and pregnant 😢 I have only had the baseline scans . Thank you for your message ❤️ xxx

[Millbanks in reply to Natasha2012]

I know what you mean - I feel like clinics are always pushing us to spend money.

Are you with the NHS? I was for a bit and they said the same. With my private clinic I really pushed them to do what I wanted. I am paying for it after all....

Ugh yes the drugs really do make you feel pregnant - it's so cruel. But as I say, you're not out yet xx

[Natasha2012]

no I can’t get funding on the nhs . I even had to ask for a progesterone test on transfer day and they said they don’t give feedback on results as it’s synthetic progesterone ? So they don’t check my hormones at all and when they do they can’t comment on it . I just don’t know what to do . I don’t want to be told I’m ok when I’m not . I will be having it out with the consultant I’m not happy at all at the lack of care xx

[Millbanks in reply to Natasha2012]

That does sound a bit odd TBH - I would defo have it out with them! My clinic checks progesterone on the day of transfer as standard - so it can be upped the same day if needed.

I would consider looking at other clinics too if that's an option? xx

[Natasha2012 in reply to Millbanks]

did you change clinics or just protocol with the same clinic? We ended up moving away from the clinic aswell so logistically it would work better to change clinic I just worry about starting again from scratch xx

[Millbanks in reply to Natasha2012]

I started with the NHS and due to covid we had a bit of back and forth - it certainly wasn't straight forward - but I moved my embryos over from the NHS clinic to the private one because essentially they wouldn't do any of the testing I wanted - even with me paying... xx

[Natasha2012]

I see you have had lots of transfers , you absolute warrior ❤️ how did you get to the bottom of what was up ? Xx

[Millbanks in reply to Natasha2012]

Ah yes! Thank you ❤️ It was a long road for us - but we did get there in the end!

I had several things tested to get to where we needed to be:

ERA test - which pinpoints the exact window of implantation (in hours from when you start taking progesterone) - mine was out by 12 hours which is a hell of a lot. However this alone wasn't enough to make it successful.

PGT-A tested embryos - we had 9 in storage so rather than just keep putting them back I wanted to be sure they weren't any genetic issues with the ones we were using that would cause them to not implant or miscarry. (we ended up with 6 normal so also think that wasn't the main issue).

NK cells / immune system bloods - I think this was the key for us - my natural killer cells were very high so essentially attacking the embryo as soon as it was transferred. So they just never stood a chance. The last transfer we added steroids and intralipids to lower my immune system and it worked! I think all those things combined really.

xxx

[Natasha2012 in reply to Millbanks]

Thank you so much for this info ❤️ I know in my heart our little one is waiting for us I just need to get to the bottom of what’s going on. I’m going to ask them to test for everything . I feel like I’m going to need another egg collection tho as we only have one C grade left . Congratulations , you deserve it and I bet it’s all the sweeter for you , enjoy your pregnancy xx

[Millbanks in reply to Natasha2012]

That's exactly how I felt - I didn't really care how long it took because I really felt it would happen (or maybe I was just not ready to think about what we would do if it didn't...)

I ended up having 4 egg collections over 2 years - but I would do it all again in a heartbeat. There is a lot that you can try if you're struggling.

Feel free to PM me any time if you want to chat or have any questions!

Aww thank you - he's actually already nearly 2!! And he's genuinely the most wonderful, sweet, hilarious little thing xx

[Natasha2012 in reply to Millbanks]

Oh sorry I thought you were pregnant! 😂 I love boys! My son desperately wants a little brother and asks me all the time for one 😢 xxx

[Millbanks in reply to Natasha2012]

Oh bless him! xx

[Madelaine84 in reply to Millbanks]

Hi Millbanks

When did you stop taking prednisolene if I may ask? We are in similar situation they told me to stop at 3 months which is 1 week from now but I’m just so worried that once I stop my body will start attacking the baby.

[Millbanks in reply to Madelaine84]

So I tapered off from 11 - 15 weeks. Reduced by 5mg per week then stopped at 15 weeks.

I think you are meant to taper so I would check with your doctor. But your baby will be fine when you stop xx

[Natasha2012]

I did test positive for HPV in October with my smea r wondering if this is connected . I cramp massively after transfer and then it goes after a couple of days x

[Millbanks in reply to Natasha2012]

I think if your clinic weren't concerned then it probably won't have an effect. xx

[Meeandembryos]

It's not over yet. Some embryos take longer to implant which is why your official test date is given. Hang in there keep the hope.

[Natasha2012]

I’m trying to keep in mind my embryo was a slower developer anyway according to the lab and was only an expanding embryo on day 5 when it was thawed ❤️ xxx

[Madelaine84]

Hi Natasha,

I had 5 transfers - first 3 BFN. Number 4 i had 5 mg of prednisolene added and intralipids - BFP unfortunately it ended at 6 weeks. Number 5 I had 25 mg if prednisolene added and currently im 11 weeks pregnant. I should be weaning off the prednisolene from next week however I’m terrified if the baby will be ok. First 4 embryos were genetically tested and my clinic kept telling us after each failure that it’s probably due to embryo even though they were tested 😠

[Natasha2012]

my second transfer has failed so now I am looking at what I can do going forward . What tests did you have if you don’t mind me asking ? My clinic don’t look at testing they only seem to want to do the ivf so I need to know what to be asking for … what does the prednisolene do ? And congratulations ❤️❤️❤️❤️ xxx

[Natasha2012]

just seen it is to help suppress immune responses and inflammation. I will definitely be mentioning this . I’m paying an absolute fortune for all of this so I want them to throw everything at my next cycle . Xx

[Madelaine84]

Thank you Natasha 😊 I’m still worried every single day.

First 4 transfers were abroad and all embryos were genetically tested.

Transfer No 1 - BFN I was prescribed cyclogest, estrofem - they saw a little polyp on ultrasound but they said it’s so small it’s unlikely it will cause an implantion failure.

Transfer No 2 - BFN they have added clexane injections

Transfer No 3 - BFN I had hysterescopy done to remove the polyp, still didn’t work

Transfer No 4 - I had natural killer cells test done which came back normal although a bit on higher site. So I have asked the doctor if I can take prednisolene but she was very much against it as she said it there is no need for it and she basically doesnt “believe” in it. At the end she agreed to 5mg which is very small doses and intralipids. That resulted in a positive test however I have miscarried at 6 weeks. What annoyed us was that after every single failure they were telling us that there was something wrong with an embryo(all genetically tested) and pushing us to do another transfer without searching for the cause of the failure.

Next cycle we have done in UK - we gave them all the information from the previous failures and I have asked the l doctor if he can prescribe me prednisolene . He agreed and gave me 25mg of prednisolene, cyclogest, clexane and baby aspirin ( as per intralipids he said “don’t bother” ). That resulted in positive test (embryo wasn’t tested this time). I’m just hoping and praying that this baby decides to stay this time.