Treatment after Implantation Clinic Results

[Sabrina2023]

Hi

I was wondering if anyone can share what treatment they are on after attending the implantation clinic in Coventry and seeing a Reproductive Immunologist. I suffer from RIF and took steroids and blood thinning injections during my last FET. I have one last attempt and wondering if I should attend those clinics.

[DianeArnold Partner Nurse Fertility Network UK]

Hi. Please reply to this post by PM if mentioning clinics by name. Thank you. Diane

[Hidden in reply to DianeArnold]

The Coventry clinic is a university+ NHS research based clinic affiliated to Tommy’s charity that make no monetary gain from patients so not sure why it would be a problem to openly discuss this as it may be helpful to more than one person?

[IVFat40]

Hi hun, I found them wonderful, I saw Dr Brosens and was part of their research study. They found I had high uterine natural killer cells and suggested steroids and also the scratch. I'd had 5 previous transfers fail (7 embryos), and the first transfer after seeing Dr Brosens is my 13 month old little boy. Found them so knowledgeable and also willing to talk and explain things.

[LSandJ in reply to IVFat40]

Hi, can I ask how long you took steroids for? I am successfully pregnant after taking them, but am 9 weeks and clinic is saying reduce at 12 weeks. However, I've since been diagnosed with psoriatic arthritis and am worried if I stop them it could cause an issue??!

[IVFat40 in reply to LSandJ]

Congratulations! Yes from memory I took them till about 12 weeks (may even have started reducing from 10 I think). The worry never ends does it. I didn't have any issues coming off them at all myself.

[Sabrina2023 in reply to IVFat40]

Hi, thank you for your reply. I hope you don’t mind me asking, when did you start taking steroids and at what strength?

[IVFat40 in reply to Sabrina2023]

I took 20mg daily, and from memory started the day before transfer 😊

[LSandJ in reply to Sabrina2023]

I am also taking 20mg (prednislione) started on day 3 of cycle!

[Trytryandtryagain84]

I also had a good experience - Prof Brosens put me on sitagliptin for 3 months before my next transfer. My next transfer involved DE rather than my own eggs so another variable but I felt like the sitagliptin definitely changed things in my natural cycle. I am 17w pregnant from that last transfer.

[Flora14 in reply to Trytryandtryagain84]

Can I ask what the sitagliptin was specifically for?did they say and explain What test was done to determine why you need it and what it would do do how help? Thanks

[Trytryandtryagain84 in reply to Flora14]

He mentioned uterine lining which had come up in one of the biopsies he'd conducted. It was a test drug for recurring implantation failure but the drug has had success in recurring miscarriages.

[HedgehogMad]

I saw Prof Brosens for RIF, he put me on sitagliptin but I had 2 chemicals after this so it didn't make a difference. He did caveat by saying that all their treatments are experimental and have no firm evidence so bear that in mind if you decide to see them. He did say to me that it is persistence and if we keep trying then we will have success eventually xx