Prednisolone and Neubogen advice

[Babymagic37]

Hi lovelies!

Can I get some feedback on the following:

1. Prednisolone; and

2. Neubogen

My doctors advised I take these for our next embryo transfer. Anyway had these added to their IVF egg donor protocol:

- Any side effects?

- Success after use?

Thank you! ✨

[LifetoCherish]

hi lovely, yes I used prednisolone on my last transfer June 21 and we were successful. The previous transfers failed and I wasn’t using that drug for those. I said from the beginning to the doctor I wanted that steroid as I knew it would help me (5 auto immune diseases; hay fever; ibs; psoriasis; eczema and suspected endometriosis). I haven’t used the other drug.

We are looking to start another transfer (baby nearly 1 years old) with one of our remaining two embies and the same protocol will happen, so the same steroid. Doc said to stick with this drug as it seems to have worked for me.

Best of luck x

[Babymagic37 in reply to LifetoCherish]

hello! Thank you so much for your reply. Did you use it for NK cells too or just for autoimmune conditions? Did you have any side effects from it?

Thank you! ❤️

[LifetoCherish in reply to Babymagic37]

Hiya! Well they never specifically said NK cells, but they took a sample from my womb and said something was slightly imbalanced (never got a clear answer on that one when I asked) so that’s why I got given it. But I believe it was for NK cells. The side effects for me were moon face and a big appetite! Wanted carbs constantly but then pregnancy apparently everyone does so I think it tripled it for me.

Other things I did for that transfer was use a thrush pessary (for frozen rounds there’s studies it increases chances of success) and liquid probiotics. I also was sedated for the transfer as I’d get too much adrenaline (sweaty hands etc) and they know that if a body is pumped with adrenaline the reproduction system turns off and survival mode kicks in. So I told them this and they agreed for that reason to sedate me. It cost me more but I’ll be doing the same this time 🙏

Hope that info helps you xx

[Babymagic37 in reply to LifetoCherish]

hello! I’ve heard a side effect can be increased appetite! 😬 can I ask what dosage you were put on and when you started taking them? (eg during or before cycle). So sorry for all the questions, just trying to get my head around it all. I’m contemplating intralipids too altho the thought of it does freak me out a bit!

That’s really interesting about the thrush pessary. Was it the caneston one? Because I’m sure I’ve read something about that. I’m on a vaginal and tummy probiotic aswell as a prenatal and I’m trying L’arginine to help my lining. There’s so much you could do! It’s hard to know when to stop.

I didn’t know that about adrenaline impacting the reproductive system either! I tend to be pretty calm by the time I get to transfer, I think I’m just so relieved to have got to that point I’m happy for them to do whatever they need! Have you got a date in mind for your next transfer? x x

[LifetoCherish in reply to Babymagic37]

That’s ok, we are all here to help each other 😊

So I was put on 10mg a day, so 5mg in the am and 5mg in pm. The hunger was alot but I do tend to have a bigger appetite naturally anyway

If you Google thrush pessaries for FET you’ll find the few studies and can make a decision if that’s right for you or not.

My transfers were painful (in the minority there) so I was on edge and dreading them after the first go, hence the adrenaline. I’d read years ago that the body turns off all necessary systems when in survival mode so I checked with them and they agreed it prob best to put me under.

We are hoping to start in March 🙏 xx