*sensitive* second pregnancy after nk cell treatment?

[Zebedee1971]

Just wondering if anyone on here has managed to have a second baby naturally after having nk cell treatment previously?

I was lucky enough to have my first child in 2021 after a 3 year struggle and thousands of pounds spent on nk cell treatment. We are now trying for baby 2 but after our visit to the clinic today, I can already feel my anxiety building... And my credit card has taken a battering already.

My gut says if I've been pregnant before then surely my body will know how to stay pregnant if I conceive again?? But the doctor seems to think I'll need all the drugs again. The idea of taking steroids again fills me with dread. I really don't want to go through it all again 😔

So I'm curious if there's anyone on here who's pregnant with baby 2, and if this was naturally conceived or if nk cell treatment was needed again?

A bit specific I know, but thought I'd ask

[Maui2020]

Hi Zebedee, congrats on your baby. This is not answering your question but I thought worth mentioning. I had an ivf baby in 2017 with no extra drugs or testing. On our subsequent tries for a sibling, even using our 2017 embryos, we didn’t manage to get any to stick. We then immune tested at our 8th try and I’m now holding my newborn. I’m thankful it worked but still a little perplexed how I’ve had one Ivf baby with immune therapy and one without. The explanation I was given was that I must have had a particular strong embryo the first time. My Dr was very resistant to me immune testing in the first place as it wouldn’t have made sense to have high NK cells given I had a pregnancy, but they came back very high. It’s such a hard decision as it’s not well understood. But it seems possible to not be consistent from one try to another. Wishing you lots of luck xxx

[Jess1981]

Hey lovely congratulations on your baby 🥰 I had my first child with my husband in 2019 after a 7 year struggle due to a delayed diagnosis of my endo and 3 surgeries. I had my nk cells tested via blood test- mine were 12% under 10% was considered normal. My specialist didn't think I needed treatment I was skeptic at first at the time we had unexplained infertility. But he did agree to steroids 10mg daily if I conceived till 12 weeks. I took them with our first daughter who arrived safely in June 2019. When she turned 1 we decided to try for baby no 2. Of course it soon become covid and steroids were not allowed. I had a late loss of our second daughter Amelia and 2 early losses . I was referred when I hit magic no 3 for miscarriage testing - no reason found but the specialist did agree to steroids again I had some with Amelia but refused with the 2 other pregnancies. I can't say for sure whether my body needed a longer break after losing Amelia or if the steroids were the winning factor but that pregnancy I had steroids with ended with our daughter Eliza who was born in February who is coming up 6 months. . I feel the steroids were helpful with having both girls especially as I have endo and bleed every pregnancy . Everyone's experience will differ and no one can sway what is right for you to do. It's a tricky decision to make. Especially if they make you feel unwell.

I wish you the best with whatever you decide to do. Xx

[Eternalwarrior]

Hello lovely,I am afraid I cannot answer your question but I am very interested to hear what others can say. I have a very complicated medical history and had four miscarriages in the first trimester and one late loss in the second trimester, all chromosomally normal. My miracle baby boy is 4 months old now and that transfer and pregnancy I was treated on a very high dose of steroids (30 mg), hydroxychloroquine, heparin and aspirin. I just have one embryo left which is not very good quality (a C grade embryo) and I don't think I could go through another IVF cycle. I am older now too and have severe endo. So, that would be our last chance really. I asked my clinic if we decide to go for a FET in the future, if I would need the autoimmune treatment again. I have lots of problems with my bones and have had a few fractures so steroids do me no good... and I really dread them for that reason. They said it is up to me and sometimes women can get lucky and have a successful pregnancy afterwards but in my case, they wouldn't recommend it.

So, for me it will be a very hard decision to make, as our last embryo will be our last chance if/when we decide to go for it. I would love to hear some positive stories from others though!

Good luck with whatever you decide to do xx

[SCHNOW]

Hi, I am wondering whether you have managed to have your second baby without NK treatment? Thanks!