Anyone had Low AMH (<1pmol/L) but succeeded with Letrozole only?

Hello lovelies,

I was wondering if any of you have/ or know someone who has had really really low AMH (less than 1), but managed to conceive using just Letrozole only (no other stims, meds, or IUI)?

Also, have you heard of/ seen “Egg/ cell shells”, or deflated follicles after ovulation?…

So basically… while waiting for private help to kick-off on 13th July, I have been on a low dose (5mg) cycle of Letrozole. Just thought I’d give it a go meanwhile, to see how I respond to the drugs (before going hardcore at Private clinic, and finding out it doesn’t work for me!). I was advised to take it on days 2-6, but I sneakily went for Days 1-5 (because I came on the night before and didn’t want to leave it too long). Had a scan today on cycle day 12, expecting a measly AFC (had 5 at my baseline). So… they told me that it looks like I have already ovulated (just) - and 1 egg from each ovary, with a further 2+3 smaller follicles (which of course won’t mature now anyway). I felt some strange twinges yesterday morning, on both sides, which I’ve never felt before - so now wondering if this was it happening?!. She was very confident that we were looking at the “shells” of the egg cells/ deflation of the follicles. I have a further blood test next week to check progesterone, to confirm if I ovulated (I know it’s not an exact science though).

I really don’t want to get my hopes up, but I’m shocked (and trying not to get excited) that I may have produced an egg with such low AMH - however I’ve never heard of seeing egg shells on scans (I’m new to all of this, so not very well studied!). Anyone ever heard of this or seen the “shells” on their scans?

Thank you xx

Lulu 🌺

[Hope086]

Hello Lulu,

I was diagnosed with low amh as well and I tried Letrozol and Clomid for a couple of cycles. I produced at least one sometimes more follicles with the meds. My doctor told me it's time to move on with IVF at one point which was also unsuccessful so far.

I would say it's definitely worth a try but with low amh the quality of eggs is usually not that great anymore (although I'm only 35 started meds at 33). I would recommend reading the book "It starts with the egg". There are many suggestions on how to "pimp" those eggs with supplements like dhea. Best of luck to you.

[Hidden in reply to Hope086]

Hiya,Thank you for responding.

Really sorry to hear the IVF journey hasn’t yet panned out. I’m keeping my fingers crossed for you that it does.

I’ve actually just bought that book, although haven’t started reading it yet! I know what you mean about quality - I’ve just turned 36 and had led quite a clean life, so really hoping that quality will not be an issue for me. Although I know that we are looking at the dregs of the pond and so it may not be great.

There is so much debate about the AMH test around quality as well… some say it’s not representative of quality and some say it must be, because it has improved for some people with the right intake. I’m hoping it’s more about seeing an increase when the follicle count increases, or mature follicles surface and so AMH emissions are higher. Won’t know until we get them out and I have a look I guess. That is the part I am most worried about 😢

Good luck and if you ever find the magic baby dust then send some my way!!

Thanks hun,

Lulu x 🌺