Low AMH: interesting course of treatm... - Fertility Network UK

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Low AMH: interesting course of treatment. Anyone else had this?

jdiraus profile image
16 Replies

Hi all you very knowledgable lot

So we are looking at foreign clinics (providing Boris can let us back into the country once we are done!) and have looked around at a few from Greece and a few from Czech republic.

One Greek clinic offered a very interesting course for those with low AMH just like us which we had never had offered to us before so I thought I would post it and see if anyone has had a similar course. The clinic said that for low AMHers they recommend 2 cycles of stimulation followed by one transfer. Essentially you would get two egg retrievals back to back and after the second you would get transfer of either the fresh, the frozen or a combination.

They also said that there would be no benefit in remaining on such a high dose of drugs such as my wife was on in her previous cycle (375 gonal-f) and that we should have a milder level. I have heard of this course of treatment method, but would love to hear of people's experience of this.

So anyone gone down this route? Are there clinics in the UK that offer this course as well - particularly given that we may be about to go through another bloody covid wave and foreign travel would be restricted.

Let me know your thoughts

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jdiraus profile image
jdiraus
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16 Replies
Rumi40 profile image
Rumi40

Hi, im on a similar plan in the UK with a natural/mild IVF clinic in wimbledon. i am meant to be having 3 mild IVF cycles back to back with the 3rd cycle including a transfer. however last week i went in to collect my two eggs only to be told i have ovulated with one of them. im not impressed. im on a low dose with a short protocol too.

jdiraus profile image
jdiraus in reply to Rumi40

Hi Rumi40. I'm sorry to hear you've not had much success. Thanks for sharing. It seems a more common treatment than I first thought. I hope that your next cycles prove more fruitful. Good luck with your process.

DianeArnold profile image
DianeArnoldPartnerNurseFertility Network UK

Hi. Please reply by private message if you need to mention clinics by name, to avoid advertising. Thank you. Diane

luckysb profile image
luckysb

Hi there jdiraus,

That sounds a bit like a duo-stimulation protocol. I’m just waiting to go ahead with this in London, will pm you where.

I hope that helps 😀

Marisa32 profile image
Marisa32

They are right. High stims won't do much for low AMH, mild or natural IVF is best. You may need multiple cycles to get one or few embryos.

Nadia09 profile image
Nadia09

Hi, Thanks for asking this question. I had my first round of IVF in Denmark and they were of this opinion to have fewer eggs produced but of good quality. So they put me on Gonal F 300 iu. They were hoping for 1 egg and 2 would be a bonus. I produced 4 eggs and they transferred 2 embryos 48 hrs after. That cycle was not successful. Due to the pandemic and stress of travelling i decided to stay in UK for the next round. This time they advised Gonal F 300 + Menoopur 150 iu..short protocol. I produced 4 eggs, which became 4 embryos. We used an embryoscope and had 1 blastocyst which did implant. However foetus stopped growing at 6weeks. Sad yes but also excited to know i could get pregnant. I`m 43 years old. Has anyone been placed on a similar protocol? I`m torn between the two differing theories.

Best of luck with your IVF journey.

jdiraus profile image
jdiraus in reply to Nadia09

Thanks for sharing your journey Nadia09. It's great that you were able to get so far with it. I'm sorry you were not ultimately successful but great that you are encouraged by the results. Keeping positive is part of the journey.

Best of luck to you too.

NurseMiaMia profile image
NurseMiaMia

My AMH is low: 0.69. Doctor had me on Follistim 300 units daily for about 3-4 days then he changed it to 450units daily and Menopur 150 units daily. Stimmed for an entire 2 weeks. 13 eggs collected. 9 matured, 9 fertilized and out of those 9, 1 transferred at day 5 fresh. 5 remained to be frozen.

jdiraus profile image
jdiraus in reply to NurseMiaMia

Wow that's really impressive. Congratulations. We haven't heard of Follistim. Must do some Dr Googling!

JoyfulStar profile image
JoyfulStar

There is a clinic in London that specialise in mild IVF which is basically what you are describing. They even have open days online which you can attend. They offer back to back cycles as well. I can PM you the details.

jdiraus profile image
jdiraus in reply to JoyfulStar

Hi Joyfulstar - that would be great. Thank you!

Fatu1 profile image
Fatu1 in reply to JoyfulStar

Hi JoyfulStar can U send me the clinic name pls

DJ202 profile image
DJ202 in reply to JoyfulStar

Hi Joyfulstar, could you send them to me as well please? Thank you :)

Ivfgotadream profile image
Ivfgotadream

I was with the clinic Joyful Star alluded to and had twins

jdiraus profile image
jdiraus in reply to Ivfgotadream

Thanks Ivfgotadream - did you do back to back cycles? I'm interested in that course of treatment and how successful it is.

Ivfgotadream profile image
Ivfgotadream in reply to jdiraus

Cycles 1 and 2 were back to back then had a month off as hormones all over the place then covid lockdown so ended up being 3 months later x

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