Progesterone levels for viable pregnancy any input?

[StressedIRIS]

Hello, i am wondering if anyone or anyones clinic has tested their progesterone levels after embryo transfer and maybe after positive pregnancy test and what would be the level to have a progression of pregnancy in IVF???

I read A STUDY that 14 dpo and positive pregnancy test should be above 300 nmol but then i saw a lot of posts saying that anything above 100 nmol or even 40 nmol is good. However i am wondering with IVF as we do get progesterone externally what they should be.

I would really really appreciate it.

[Loma1]

Hi MariaI’m not sure about the study but my personal experience is this:

My consultant said above 30 nmol/L is good - and was very happy with having 60+ nmol prior to implant and on positive pregnancy test.

Are you sure the units were nmol/L for the 300 value?

I’ve attached the progesterone ranges from my lab in case it helps X

Images are hidden by default on this community. Learn more

Show imageRemember my choice on this device

[StressedIRIS in reply to Loma1]

Hello! Thanks for replying.Yes the study indicated that at day 14 after embryo transfer and with a positive pregnancy test women with progesterone levels above 350 nmol went on to have successful pregnancies whereas women with levels at 150 nmol had miscarriages and so on. However i only found this one study. Probably with ivf as you supplement progesterone it should be higher but k really dont know. Really thank you for replying.

[Loma1 in reply to StressedIRIS]

Can you share the study please?

[StressedIRIS in reply to Loma1]

Hi, the study is : pubmed.ncbi.nlm.nih.gov/155..., this is from 2005 and i am not sure when was the last dose of progesterone before testing.

I also found another study that reports lower levels and this is from 2017. : pubmed.ncbi.nlm.nih.gov/287....

So not sure which one is the correct! Any experience anyone?

[Loma1 in reply to StressedIRIS]

I gave my personal experience and have made it to 8 weeks. I thought you wanted reference ranges so I shared. The second study gives the ranges shared by several research sources via simple searches and is consistent with my consultants advice.

Although I could choose to accept the alternative and await my impending miscarriage as predicted by your first study.

Sorry my reply failed to give you the answer you we’re looking for.

[StressedIRIS in reply to Loma1]

Hello Loma1. First of all congratulations! That is amazing news and well done! Thank you so so much for your reply. I agree with you and obviously your consultant wouldKnow more!

And of course in any way and form I am Not saying that i believe the results! You are an example that they are not reliable! And honestly thank you so so much for proving them wrong. I was worried about progesterone levels in general and In any case i didnt want to scare anyone as i am also scared!

My apologies if this study upset you in any way! I think you are proof that its rubbish!

Please enjoy your pregnancy! And again congratulations

[Loma1 in reply to StressedIRIS]

Thank youI know you had no intention of upsetting me - all the studies etc are very conflicting.

I usually only share personal experience for this reason and so if progesterone is a concern for you and would consider alternative ways - vitamin C delays the break down of progesterone in the body so can be helpful as a daily supplement to increase serum concentration. I also purposely eat progesterone rich foods.

Good luck

[StressedIRIS in reply to Loma1]

Many many thanks!!!! I really appreciate it and obviously you helped massively! As i said before this is massive proof of the opposite of that study. Please remain positive and enjoy your pregnancy!