Buserelin vs Gonasi

[Anonymous501]

Hello. I'm currently going through my first egg freezing treatment and have been given Suprefact Buserelin as my trigger injection to take in a few days. My sister who is at a different clinic but had similar blood levels/follicle count as me (and is 18 months younger), so I was wondering what the difference is with Buserelin and Gonasi? Or if anyone has had experience with both?

[Millbanks]

Hi there, I've had both triggers. Physically there was no difference for me and I think they are both the same drug essentially - so I think it is a preference of the clinic. The only difference for me was that for my first Gonasi trigger I had 10,000 and it wasn't quite strong enough so the next time I had 12,500 and it was perfect. How much have they given you? x

[Anonymous501 in reply to Millbanks]

That's good to hear. I've been told 1mg but I'll go in the following day so they can see if I need more.

[Gemgem84]

My clinic changed mine from gonasi to buserelin due to OHSS. The gonasi is Hcg which can make OHSS worse so this may be why?

[Anonymous501 in reply to Gemgem84]

Ah. My clinic said that I was at risk of OHSS. Did you do more than one cycle? I.e have you experienced both triggers or did they change it during the same cycle?

[Gemgem84 in reply to Anonymous501]

No this is my first cycle but I started with OHSS symptoms on the last day of stims so they changed my trigger and said I would have a freeze all, gave me cabergoline to take for 8 days and fragmin injections to start 2 days after EC until further notice. I was on a low dose of Meriofert too - only 150 then increased to 225 after 7 days and that kind of sent my ovaries mad.