New interesting therapy for ICSI/IVF

[SunnyDream]

My greetings, forumers!

A few days ago I've read somewhere an article about a new and unique method to get pregnant in your 40s with your own eggs. Unfortunately, it is not impossible for me as I use DE, but there are many of you whose OE are still alive and can be used. I hope this may help.

I just copied the text from an article for you to read.

@@@One of Ukrainian Centers for Human Reproduction offers patients who are above 40 and for those, who suffer from low levels of AMH, an innovative program that makes it possible to get pregnant with their own eggs. The donation of mitochondria, or, as it is also called, mitochondrial replacement therapy, is an innovation and a breakthrough in the field of ART and the fertility treatment. This program gives women, who underwent numerous unsuccessful IVF cycles, aged 40+, (patients with low mitochondrial functional activity), an excellent chance to give birth to a child who shares a genetic relationship with her and her partner. How is this possible?

The mitochondrion is one of the most important components of any living cell, including the egg. In simple words, the mitochondrion is the cell's energy station. Essentially, its work consists in supplying the cell with vital energy for its normal functioning.

Women that went through multiple unsuccessful IVF attempts, as well as of older reproductive age, need to restore oocyte mitochondria in order to successfully become pregnant. A woman can become pregnant only if there are functionally active mitochondria in her oocytes. Donation of mitochondria will allow thousands of hopeless women to give birth to a healthy child through IVF using the mitochondrial donation.

To carry out such a procedure, an egg donor with a high functional activity of mitochondria (a blastocyst production rate of 70% or more), a patient (willing to get pregnant), and sperm for in vitro fertilization are required. Healthy functionally active mitochondria are taken from a donor’s oocyte and integrated with the patient's cells. Next, fertilization with sperm and transfer of a healthy embryo into the patient's uterus is performed.

Mitochondria donation is a unique assistive reproductive technology, which is basically the implantation of healthy and functionally active donor mitochondria into the cells of an infertile patient, that provides the patient’s cell with the necessary energy and contributes to a successful pregnancy.

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[MRSrob]

Wow.. that’s like a whole massive info of science technology. But I don’t think it’s available in Asia country yet.

[SunnyDream in reply to MRSrob]

Unfortunately, not. I know the only one clinic that conducts this procedure and it is in Ukraine.

[MRSrob in reply to SunnyDream]

Too bad. But it’s a good info tho.

[Elfine]

Interesting. But bear in mind that the mitochondria has DNA too.

[SunnyDream in reply to Elfine]

Hello Elfine. Actually, it hasn't. It only gives that necessary energy to the oocyst and helps with developing an embryo and make it stronger. I talked to the doctors about this and they explained everything. Mitochondrial DNA and human DNA are slightly different things. DNA is in the core of the mitochondria, which are not used for donation. Therefore, genetically, mitochondria have no effect on the embryo.

[Elfine in reply to SunnyDream]

Thanks for the info! Quite complex. I was thinking in line of genetic diseases that are carried in the mitochondrial DNA as that might be something to look in the donor but if they don't use it, it has no sense. Thanks!

[SunnyDream in reply to Elfine]

If I could only know about this treatment earlier...

How is your journey hun?