Thoughts on - Preimplantation Genetic Testing for Aneuploidy

[Eeek]

Hi

After an early miscarriage (low and slowly increasing HCG levels for over a month) from my first round of ICSI on NHS in October, we went back last week for a private consultation.

Dr gave two options, short protocol or do the same again, long protocol. We decided since I got a positive, we would stick to the same long protocol. Then I brought up the subject of Preimplantation Genetic Testing for Aneuploidy. My husband seems keen on it because he thinks it would stop the heartache of a positive that would not result in a viable pregnancy again, but it is a lot of money we don't have. I also know it doesn't guarantee a successful pregnancy. I'm confused. Clinic just say it is up to me to decide, which would also mean a change in protocol from last time. Anyone else been really keen to get this done?

I am 41. AMH 6. Had two embryos implanted day 5, but were not quite at the blastocyst stage. Unexplained fertility issues.

Thanks xx

[2-shades-of-hope]

It’s a really hard decision. Part of me wishes we had done it straight off, as having had a miscarriage which was almost certainly chromosomal, I feel like I am opening myself up to the same thing happening again by transferring untested embryos. We will definitely be doing it next round if our remaining frozen embryos don’t result in a baby. From what I’ve read though it doesn’t seem that they are particularly confident in the accuracy of the test and it concerns me that we would potentially waste embryos that may otherwise have a chance. Have you done any reading on it? I think the HFEA have it listed as amber x

[Scarlett13]

I decided against it this cycle due to the astronomical cost but sometimes wish I had...but then I think the test itself is not entirely accurate and some abnormal embryos have been proven to create normal babies, plus there’s a risk of damaging the embryo with the test. However, it potentially saves heartache and time, so it’s difficult. I don’t know if I’m made the right decision by saying no. Do you have enough embryos to make the cost worth it? X

[Cinderella5]

We have never considered it....well not at the time of using my own eggs. In all honesty it didn't cross my mind but I've learned that as we get older the more chances are that we have a greater percentage of aneuploidy embryos & I've researched about the detrimental effect it can have, if you even have enough to test. We only managed 3 blastocysts over 2 cycles at the age of 38/9 & amh of 7.19.....and No bfp. We made the tough decision of moving to donor egg, gave us a better chance of success but obviously no guarantees. This vs pgs made more sense financially. Have you done karyotyping? This is cheaper to check for genetic issues. I don't want to overstep the mark...but if you can/would consider donor eggs it may increase your chances significantly.xx