Clexane after 12 weeks pregnancy? - Fertility Network UK

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Clexane after 12 weeks pregnancy?

Babytalk profile image
12 Replies

Hello,

We have been so lucky and have hit the 12 week mark on our third round of IVF and successful with a FET.

But now we have a decision to continue with Clexane or not... the Consultant said the NHS wouldn’t have advised it but it’s up to us if we want to continue!

Anyone good any experience of this?

Thanks and I hope our success brings hope to everyone on the journey.

Xx

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Babytalk profile image
Babytalk
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12 Replies

Hi there and mega congratulations on getting to 12 weeks!! I’m on Clexane too (currently approaching 10 weeks) and have been on it since a few days pre transfer after many miscarriages and chemical pregnancies. I’m on it because I have Factor v Leiden heterogeneous which is a blood clotting disorder. Why were you put on Clexane? My blood specialist said the 2nd and 3rd trimester are more important in terms of me having this protection and to stay on it until 6 weeks post partum. It’s v expensive and I pay approx £50 per 10 days but for my health and baby’s safety it’s easential x

Babytalk profile image
Babytalk in reply to

Thanks Natalia. I was put in it for a mutation of the MTHFR gene, not a blood clotting disorder exactly but it is a higher risk of it. The NHS consultant has increased the baby aspirin. They will start me on the injections again at week 28. I just don’t know what to do for the best. Pros are not having to inject and have bruising on stomach for three months. Also have a prescription from the NHS for their version of Clexane so is free...

in reply toBabytalk

Sounds like you’re being well monitored and that is quite different to my condition. The baby aspirin should do the job well and as you say it’s nice to have a bit of a break from all the needles...my poor tummy 😓 hard to find a non bruised site! Good luck and I’m sure you’ll make the right decision xxx

Babytalk profile image
Babytalk in reply to

Poor you, good luck though I hope it will be worth it for you xx

in reply toBabytalk

Thanks so much 😘

Sarah_S profile image
Sarah_S

Congrats on reaching 12 weeks! I'm on Inhixa (a different version of Clexane), also for a mutation of the MTHFR gene, and currently 9 weeks. My consultant said to stop it after 12 weeks as it wasn't needed any more. A bit difficult if your consultant has said it's up to you - they are supposed to be the experts! Then everyone is left googling answers... x

Babytalk profile image
Babytalk in reply toSarah_S

I know right, but they are not ivf specialists and didn’t really take the MTHFR seriously, she knew what is was but as it’s not available on nhs I think they disregard it. Thanks for sharing what your consultant said x

DisneyJL profile image
DisneyJL

Congratulations! I think if your consultant said they wouldn’t advise it, then don’t go for it. They obviously know the increase in the baby aspirin will cover you, so give yourself a break. If they thought it was vital to continue clexane, they would have. I expect the only reason they say it is up to you, is because so many people have gone through so much with their IVF journeys, that they give patients choices to do with treatment/meds that aren’t vital but also will not cause harm, so that they feel reassured.

Babytalk profile image
Babytalk in reply toDisneyJL

Yes I agree, and it’s working. I’ve got the meds and think I’ll continue taking as if I stop and something happened I’d be broken. So hard to make the right decision

LHow81 profile image
LHow81

I took flex the whole way through my pregnancy and a few weeks after it was not a great experience as the injections are fairly painful and it does get harder when you start getting bigger! However I would have continued with them if I was given a choice it’s always better to be safe than sorry. Good luck to you x

AnnieAnnie profile image
AnnieAnnie

Hi there and congratulations! As I have the C4M2 variation, I have been prescribed clexane to start taking at EC. For this variation, as I am the carrier of the chromosome mutation, I will have to take clexane every day and up to 6 weeks following birth (should I be lucky enough to conceive on this cycle and carry to full term). You are probably best being guided by your consultant and together with going with your gut instinct. And maybe ultimately it will make you feel at ease to continue and not worry what if. Wishing you luck xx

Zunia profile image
Zunia

Hi I have the same query...I was diagnosed with low protein c and s but ivf nurses say to discontinue it at 12 weeks.I m confused as there is this thrombophilia.

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