How long does it take for Synarel to come... - Endometriosis UK

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How long does it take for Synarel to come out of your system?

Kangaroodle profile image
3 Replies

How long does it take for Synarel to come out of your system? I have been prescribed Synarel to put me into the menopause while I wait for a hysterectomy where they will remove my ovaries so will go through menopause anyway. Due to Coronavirus the operation will take ages so this is to hopefully stop me being in pain all the time. I am worried about the side effects of Synarel and would be interested to know if anyone else has taken it. If so how long did it take to get back to ‘normal’ once you stopped? I would like to know that if it doesn’t agree with me I can stop and it will come out of my system quickly. Thanks in advance xx

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Kangaroodle
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Busy-Lizzie profile image
Busy-Lizzie

I used Buserelin, which is a nasal spray GnRH analogue the same as Synarel.

It's short acting, and has to be snuffed several times a day, so after the last dose periods can restart within 4-6 weeks.

Mine restarted within a month the first time I came off it and about the same the second time.

Kangaroodle profile image
Kangaroodle in reply to Busy-Lizzie

Thank you for the reply Busy-Lizzie. How was it? Did it help? How long did it take to start working? x

Busy-Lizzie profile image
Busy-Lizzie in reply to Kangaroodle

I was on Buserelin for a total of 5 years, which is unusual but was right in my circumstances. It started to work within 3 months.

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