Researchers Find Novel Mechanism Regulating Replication of Insulin-Producing Beta Cells for Diabetes Treatment

Bringing scientists a step closer to new treatments for diabetes, researchers at the University of Pittsburgh School of Medicine and The Mount Sinai Medical Center have discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas. The findings were recently published online ahead of print in Diabetes, a journal of the American Diabetes Association.

Regenerating beta cells to restore insulin production has moved to center stage in the quest for therapies for both type 1 and 2 diabetes, said lead author Nathalie Fiaschi-Taesch, Ph.D., assistant professor, Division of Endocrinology and Metabolism, Pitt School of Medicine.

“Ideally, we would be able to do this by collecting cells from donor pancreatic tissue and growing them in the lab or better yet, giving a patient a pill to stimulate their own beta cells to replicate,” she said. “In the past, this has proven to be very challenging. Our findings provide new insights into how one may be able to do this. ”

1 Reply

  • For T1 they will have to get over the Auto Immune disease before the regeneration step else it will be useless. For T2 i can understand this. Some team in Israel is also working on this from what i read last year... i am sure they must be patenting some extract from gymnema after replacing some atom :) :) -- like they replaced one molecule with chlorine in sugar and produced SWEET DDT which is patented and sold as SPLENDA to make money of diabetics :D :D

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