Medications To Be Avoided Or Used With Caution In Parkinson’s Disease
The manufacturers of these medications may not list Parkinson’s disease as an absolute
contraindication; however, better choices within a medication class may be suggested. Some
of these medications alter the brain ‘s dopamine system causing an increase in Parkinson’s
symptoms, others may chemically interact with Parkinson’ s medications and cause side effects.
This is not intended to be a complete list and additional brand names may occur for each
medication. If you have any questions about this list, please talk to your physician or pharmacist
Medications To Be Avoided Or Used With Caution In Parkinson’s Disease APDA
Medications That Should Be Avoided....list, see link below
Medications that should not be taken with Selegiline HCL (Eldepryl, Deprenyl, Zelapar) and Rasagiline (Azilect...list, see link below
Medication classes that should be discussed with doctor or pharmacist
Newer Antipsychotics:
The newer antipsychotics have a lower risk of worsening Parkinson’s symptoms. They include:
aripiprazole (Abilify®), olanzapin (Zyprexa®), risperidone (Risperdal®), ziprasidone (Geodon®), Lurasidone (Latuda®), iloperidone (Fanapt®), paliperidone (Invega®), and asenapine, (Saphris®). Clozapine (Clozaril®) and quetiapine (Seroquel®) have the least risk of worsening symptoms.
Antidepressants:
Some agents within this class may worsen PD symptoms, increase confusion, or interact with some of your PD medications.
Antihistamines:
These are found in cough, cold, allergy, and sleep medications. When taking these medications, the elderly are at an increased risk of the following side effects: blurred vision, confusion, constipation, urinary retention, and dry mouth. The newer antihistamines loratadine (Claritin®) and desloratadine (Clarinex®) may have less side effects than older antihistamines. Cetirizine (Zyrtec®) may or may not have less risk. Topical eye or nose sprays/drops have the least risk of these side effects.
Non-prescription medications and supplements:
Some of these agents may interact with PD medications. They may not be contraindicated; however, an adjustment in the timing of the medication may be needed. For example, iron supplements may decrease the absorption of levodopa and these medications should be spaced as far as possible.
Link:
apdaparkinson.org/uploads/f...
The above tables were compiled by Maria Tan, Pharm .D. candidate and Mary Wagner, Pharm.D., MS Ernest Mario School of Pharmacy at Rutgers, the State University of New Jersey. The information contained in this supplement is solely for the information of the reader. It should not be used for treatment purposes, but rather for discussion with the patient’s own physician. For additional free copies of this supplement, please call or visit the website AMERICAN PARKINSON DISEASE ASSOCIATION
(800) 223-2732 • apdaparkinson.org
hang tough