Trials

Since 2012 I continuously tried various approaches and gauged or judged the benefit: sinemet, coconut oil, amantadine, keto diet, Neupro patches, mucuna, plus other park drug's name I cannot recall. This list could be longer. In all I never experienced placebo effect nor notable improvement. Thiamin HCI is sent from heaven by the grace of Doc Costantini.

[park_bear]

I have my own such list, and I have to agree - I have tried my fair share of things that made no difference. It seems extremely unlikely that the placebo effect would apply only to one particular treatment.

[Don_oregon_duck in reply to park_bear]

Placebo or no Placebo, are we better off after B-1?

[park_bear in reply to Don_oregon_duck]

yes

[lempa_nik]

The placebo effect is triggered by mental expectations. Yet I believe that RoyProp--perhaps the first to try the high-dose thiamine in this group--was taken by surprise when it turned out to relieve his constipation. If true, this is unlike the placebo effect.

[Don_oregon_duck in reply to lempa_nik]

I started on thiamine because Roy said it helped his constipation. While I was waiting for a change in that area, one day I realized that I had so much more energy. I wasn't expecting that result. I still have some constipation issues but maybe that will change later.

I don't believe that would qualify for a placebo effect.

[cjsg]

I have been out of the loop for several months and missed the whole Thiamin issue. So what do you take and is it from Life Extension? I will only take that brand of supplements.

[Hidden]

Vitacost vitamin B1 (as thiamin HCI) 500mg, easy swallow capsules