Experiences with

Sinemet

Just curious if anyone has been prescribed or is taking Sinemet?

Zandopa taper-easier than sinemet? A recent post discussed tapering sinemet and it’s risks. Anyone have any insight on tapering Zandopa as the primary treatment? Is it lower risk of withdrawal/NMS with quick taper? Thanks

Am I the only one who thinks they are addicted to Sinemet? 13 years since diagnosis, am I still clutching at straws?

Hi everyone, maybe one of y’all will have an answer this question.Before I take my sinemet I can talk relatively well and people can understand me fairly well but less than half an hour after I take my sinemet I have great difficulty, no matter how much or little I take.

I switched from 25/100 sinemet four-five times to Rytary 36.25/145 three times a day. I am experiencing increased dyskinesia on Rytary. I was expecting it to decrease. Anyone else have this issue?

My normal medication is 4 x100+25 sinemet.3x ropinerole,1x azilect,3x pregablin,

Currently need 1/4 Sinemet tablet every 2 hours to keep muscle rigidity at bay. That's 3 tablets/day. Otherwise have trouble breathing with chest muscles so tight. Rest of body just as rigid too. Anyone had success getting off Sinemet? Really need help with this!

Anyone have success in reducing their Parkinson medication, or at least reducing the amount of medication taken each dose? Thanks

I’m also on sinemet 3 to 4 times a day. It seems to just be giving me more shakes. I also saw that another company, Banyan, has this product in both tablets and extract liquid. Has anyone tried any of these? Any recommendations?

Sinemet 100/10

Basically my mom has been on the same sinemet dose since diagnosed with Parkinson’s in 2016 (1 sinemet every four hours and 1 azilect). So my moms doctor has prescribed nourianz and increased her sinemet from 1 tablet (25-100) every four hours to 1 1/2 tablet every four hours.

It seems that he's always hot and I'm wondering if it's another side effect of cbd, or maybe it's from the sinemet?

I was originally prescribed 25/100 3 tablets per day (sinemet) 2 years ago. RH tremor was my only major symptom at that time. After 2 months of nausea, my body got used to the drug and my tremor disappeared.

Then, I faded out the Pramipexole, reducing by 0.26mg every 10 days until down to NIL and added Sinemet ER 25/100 once a day and Sinemet 25/250 tds. I was due a neuro appointment this week, but he has vanished until November.

I am on sinemet 100/25 tds, selegiline, zinc, vit d, vit b1, coq 10, SAME, resveratrol, mucuna, magnesium n pramipexole of which I take mg n pramipexole at night. I don’t take mucuna every day but for the rest, is there any ideal time? Like dopamine should be taken empty stomach before meals..

I was diagnosed with PD 2 and a half years ago and since May 2021 have been taking (l-Dopa) sinemet plus 125mg tds (0800, 1300, 1800).

Initially I had some relief when I took a dose of Sinemet. Neurologist suggested increasing dose (low) to 4x daily. After 3 weeks symptoms seem worse. Haven’t actually seen neurologist he made these suggestions after talking to my psychiatrist. All communication with them has been by phone.

Maybe up the dose of Sifrol and dump the Sinemet. I'm only on 1mg a day Extended Release.

In December started Sinemet 25/100 X1 day , then increased 2X day. Then instructed to increase 3X day. I had a lot of difficulties sleeping so decreased down to 2X day. It has had positive effects on my symptoms except the tremors.

Are there no other medications to try or even an increase of the Sinemet? I just worry that if he is taken off the medication we will just be forgotten about. As it is he’s never met either the consultant or the Parkinson’s nurse.