Dear C25K users, I am 68 and asthmatic as well as having a prosthetic knee, I have some osteo in my joints as well, painful and not much fun. I am a retired RGN so have some knowledge of medicine. I find I am losing muscle strength in my arms and legs, and have bought a bike which is quite difficult in this area as it is take no prisoners on the road. I would like to get fitter, and lose wieght, and feel I should have the energy. Is it all too late or can I tailor the programme for my age and infirmities, isn't that a horrid word. I still work, though now, for myself and am fairly, no correction very, sedantry. I wonder if the Fostair inhaler is making things worse as I have packed on weight since I started it. I hope someone out there can give me some hope.