30 days of Zanu

[Nana1961]

Hey y’all,

Just completed first 30 days of Zanu! Feeling good. Lymphnode pain minimal, more energy!

Lots of bruises, a few rashes, nausea, all manageable!

WBC is now 258k Hgb 8.2

Feeling much better!

[Newdawn Administrator]

That so good to hear seeing as I’m starting Zanubrutinib next Thursday 😊

Newdawn

[Nana1961 in reply to Newdawn]

I was so scared to start but so glad I did now!

Hope all goes well with you too!

Where are you?

[Newdawn Administrator in reply to Nana1961]

I’m in the U.K. and this is my second treatment. I’ve had CLL 12 yrs. This latest post explains how I came to be prescribed Zanubrutinib;

healthunlocked.com/cllsuppo...

Hope you continue to do really well.

Newdawn

[may04cll]

Why was Zanu recommended and not one of the other's or a

combination ?

[Richard_TX]

This is my results on Zanubrutinib (Brukinsa);

7/26/2016; WBC: 13.6 / HGB: 14.6 / Platelets: 232 / ALC: 7.9

11/8/2017; WBC: 17 / HGB: 14.6 / Platelets: 232 / ALC: 7.9

11/3/2022; WBC: 105.4 / HGB: 13.2 / Platelets: 208 / ALC: 86.43

5/11/23; WBC: 201.8 / HGB: 12.9 / Platelets: 199 / ALC: 185.66

5/19/2023; Begin Brukinsa

6/13/23; WBC: 158.5 / HGB: 12.5 / Platelets: 193 / ALC: 153.75

9/12/23; WBC: 50.10 / HGB: 14.7 / Platelets: 273 / ALC: 42.08

11/3/23; WBC: 23.9 / HGB: 14.8 / Platelets: 273 / ALC: 18.88

7/23/24; WBC: 8.9 / HGB: 14.3 / Platelets: 215 / ALC: 3.52

And absolutely no negative side effects.

[Nana1961 in reply to Richard_TX]

That’s incredible!

[Newdawn Administrator]

Just reading this very encouraging article about the clinical efficacy of Zanubrutinib;

cancer.gov/news-events/canc...

Newdawn

[Grandadsboys in reply to Newdawn]

Hi Sonrotoclax is great,no sides and levels started to return to normal,will you be starting on Sonrotoclax as well .?This also has been very good

[Grandadsboys in reply to Grandadsboys]

Sorry the first one should be zanu

[Grandadsboys]

well done,have been zanu since March ,no side effects at all,started Sonrotoclax on a slow ramp up ,I am now on 80 mill both my haemoglobin & white cell count now both normal,no side effects at all,are you going to start sonrotoclax?

[Newdawn Administrator in reply to Grandadsboys]

No just mono Zanubrutinib for now Grandadsboys.

Newdawn

[Nana1961 in reply to Newdawn]

I’d love to! However, my doctor said once I started Zanu I was no longer eligible for trial with Sonrotoclax. Are you on the trial?

[Newdawn Administrator in reply to Nana1961]

I don’t think that reply was for me perhaps Nana?

Newdawn

[Nana1961 in reply to Newdawn]

Oh yeah. Sorry.

[Grandadsboys in reply to Nana1961]

Yes I was very lucky,I get tested every week & every 6 weeks I have CT scans,even my travel expenses are paid for,luckily I only live about 6 miles from the hospital.Hope everything is going well for you

[Nana1961 in reply to Grandadsboys]

I had been waiting to start trial but my CLL progressed. My Dr said once I started Zanu I was no longer eligible for the rial combination. They were hoping to have trial open in July but got delayed.

[akirsch973]

I have been taking Brukinsa for 3 weeks and feel great. No fatigue, no nausea, no diarrhea , no bruising. Only a rash on my arm, waste, forehead and top of head. No itching, burning or pain. Quite manageable. I have an appointment with my CLL specialist next Friday.

[Nana1961 in reply to akirsch973]

That’s great!!! We are so lucky!

[Graya1]

So pleased to read this. Thank you for posting. I too have been on Zanubrutinib for around the same length of time. I’m very happy with my results . Most of the time feeling good, definitely more energy. My only negatives are very bad headaches which can last for two or three days. I also have occasions where I get up in the morning shower, dress and then have to lie down feeling really unwell. Most of the time I’m fine again within half an hour or so. I just wonder if anyone else has these symptoms?

[Nana1961 in reply to Graya1]

I’ve had headaches too! Mostly nausea, sone diarrhea, some rashes and mild abdominal pain. A lot more energy and most pain is gone.

[Danie50]

awesome! Continue to feel better!🧡🤗🤎