Side effects other than the risk of developing high blood pressure decrease over time with BTKi drugs, so you appear to be off to a good start, provided you keep on top of the nausea by taking the Zofran before you expect to experience any nausea.
Keep in mind that your WBC is the total of all your different white blood cell types. healthunlocked.com/cllsuppo... It's wise to track changes in your ALC - absolute lymphocyte count (what's happening to your blood CLL tumour burden) and your ANC - absolute neutrophil count (your primary protection against infection). Ignore percentages in your blood test reports unless you need them to calculate your absolute counts (ANC = WBC x percentage of neutrophils, etc.).
About 2 in 3 starting on BTKi drugs see their ALC initially climb, as the CLL is driven out of the nodes, spleen and bone marrow into their blood, where the CLL cells eventually die. See attached results for a few patients on acalabrutinib (Calquence), a very similar BTKi to zanubrutinib (Brukinsa).
Neil
An ALC (and hence WBC) spike is common for a few weeks after starting on a BTKi
Good to hear. I am on week 3 of Zanibrutinib. I have only had a little dizziness after taking my morning dose and it goes away quickly. I was on Acalabrutinib for 18 months and had a headache for 18 months! 😩That is why I switched. It feels great not to have a daily headache!!! Good luck with things!👩🦳
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