I previously posted that my absolute lymphocyte count was steadily growing then after I had both vaccinations my counts rose 50% in a few months. I later got covid and took ivermectin for a few days and my lymphocyte count went down from 30k to about 26.5k. I thought maybe a coincidence. Doing some research I found a video from the Japanses Dr that discovered ivermectin and he discussed all the benefits to humans such as lower blood pressure and TREATMENT FOR LEUKEMIA. He says its safe to take long-term.
Below is link to video and go to 19:30 of video.
Other medical studies I read shows it is being used for AML and helps enhance chemo and reverses resistance to leukemia drugs that stopped working due to resistance. No studies on CLL. You can also google Satoshi Omura. I am considering taking ivermectin to see if it will lowers my lymphocyte count and maybe slow the process of my CLL.
There is data that ivermectin kills leukemia cells in mice models and there is a specific mechanism of action to possibly explain why. I think the data are that much more interesting in that it discussed long before ivermectin became politicized as a miracle Covid drug.
That said, lots of things kill leukemia and other cancers in mice and test tubes that are not safe for humans. Mice lie and monkeys exaggerate, as the saying goes.
If you have a good Cll specialist I think you should present him or her the evidence you have found and follow your doctors advice. We have any number of drugs proven to kill leukemia cells at our disposal, and using an experimental drug could result in unintended consequences.
I would follow your doctors advice on this one. I am curious as to what your doctor will say, but I suspect he would not recommend ivermectin for you due to the lack of data with Cll and to the other proven options you have.
It would certainly be great if ivermectin did help control our leukemia, the more arrows we have in our quiver, the better.
Cajunjeff. Thank you for your response. I am going to ask my specialist about ivermectin. If he gives me the green light I will try it. He told me I was like wasting my time with green tea extract and turmeric. Although these seemed to slow and even slightly lower my numbers, but my gut was giving me hell from the green tea extract.
I was actually thinking of the comparison between ivermectin and green tea. Both have shown some promise in lab studies and animal studies, both are unproven with Cll. I doubt your doctor will green light ivermectin because even if it does work, no one knows what dose would be safe and what long term toxicity there might be.
It does not hurt to ask. I think are way too many confounding factors to conclude ivermectin had anything to do with your drop in lymphocytes. It sounds as if you have a good Dr and I would follow his advice.
I also had stomach issues with the green tea “extracts”, so I switched to actual the hot green tea drink, about 2-3 cups a day mostly in the morning because of the caffeine. My numbers have been under control for a long time. I gave up on the extracts a long time ago. Regarding your blood count drop with ivermectin is interesting but it’s hard to know what other variables were involved. Was it a single dosage or multiple dosages and for how long..? I think it’s a good idea to have someone following up to make sure you don’t create another issue in you gut, liver or kidneys. I am for experimenting but under some supervision. Best of luck…
The proposed mechanism for the effect of ivermectin on acute and chronic myeloid (not lymphoid) leukaemias is through the PAK1 kinase. The myeloid stem cell line is responsible for producing red blood cells, platelets and other than lymphoid white blood cell types, not B cells. Per this paper from January 2021, those leukaemia studies were on extracted leukaemia cells (in vitro testing) not in people.
My next blood test isn't scheduled for a few months, but I may make an appointment to discuss all this. My doctor is heavily involved is cll and othe leukemia studies. My main concern is I don't want to take ivermectin if it could cause a mutation or make future treatments less effective. I know this group has many better informed minds than mine and I appreciate your response.
The purpose of human trials is to find out what dose has the best effect on cancer without causing unacceptable adverse events and side effects (phase 1). Phase 2 involves more study participants to check for effectiveness on the chosen dose and obtain more information on safety, then phase 3 checks how the drug works compared to an existing treatment on an even larger group.
Following up on AussieNeil's comment, I've learned there is an apples/oranges difference between myeloid and lymphoid leukemias -- different diseases and different things help myeloid but not at all CLL. So when I see that something helps myeloid, it is like seeing that something helps gastric cancer. Not saying it couldn't help, and would be great if it does, but what a coincidence if it does, given all the covid-hype.
If such a fantastical hypothesis were true, wouldn’t that be borne out already. That is, I’m sure that some CLLer out there somewhere took ivermectin out of fear for Covid…so then they’d go to their next blood draw and be posting all over the place about this drugs virtues beyond deworming.
Hey, mleio123, so great your counts are down! But may I ask how, how much, and what form of ivermectin you took? Wondering how you got it, what form (paste?), and what dosage did you take? I give this to my dogs monthly for heartworm, so maybe you had heartworms (joking, unless maybe CLL is exacerbated by some form of parasite?) Would be great if it worked better than other things like green tea, curcumin, etc. Let us know developments. Whatever works, we all want to know. BTW, ivermectin has been around since the 1970s.
I was prescribed the ivermectin by a physician. 25mg 2x per day and they were capsule form. I took it for 3 days and felt great So i stopped. The prescription was for 10 days. Also took hydrochloroquine for 3 days.
Hi, were you given the IVM to treat Covid or to treat the CLL? I asked my Doc about it and he laughed . I was not pleased with his laughter. I am not on any treatment as my counts are very low. Thanks!
Again, IP6 is more studied for CML, as was explained here:- healthunlocked.com/cllsuppo... provided a explanation to you in your new post why hydroxychloroquine is a non starter for CLL; you'd exceed a poisonous dose in a human to kill all the CLL cells. You should have a better idea by now of what study reports on CLL, (not CML) are worth investigating further.
Also again, do you have CLL or are you trying to help someone with CLL?
The following is perhaps why the doctor laughed, because for 16 months the following has been known. There was a great deal of research into repurposing drugs for the treatment of COVID-19 before we had effective antivirals, monoclonal antibodies and vaccines. That research continued on with cheap drugs for quite some time afterwards. Ivermectin was studied after an in vitro (in a dish) study in Australia, initially looked promising - provided you ignored the fact that the initial research wasn't on human cells and would probably be toxic. The research continued on for way, way longer than it should have, due to a number of faked papers which were subsequently withdrawn. A major factor was the inclusion of a very large faked Egyptian study in meta-analysis studies which reported incredible results. That one study swayed the outcome. (The world was desperate; millions were dying each week.) Sadly, no properly conducted randomized, controlled clinical trial has since shown any effect beyond chance. I've documented the long and sorry tale here: healthunlocked.com/cllsuppo...
Individual research had folks thinking that marijuana was the fix all for leukemia because it was lowering WBC. Turns out clinical trials found that it was driving the cells from blood to nodes where they were much harder to treat. That minor drop is basically considered "stable", but do be careful.
I asked my specialist at MDA about Ivermectin for Covid.. She laughed... And, as a side note, be careful with extracts and supplements. These compounds have to be processed. Many of them through the liver.. Do not damage the liver.. Over doing it on vitamins, minerals and supplements is very dangerous. It can change the bodies chemistry and really stress out the filtering organs/system.
Hi, just joined this forum to let you know that I have experienced a similar result to you.
For the first couple of years after being diagnosed, I was on 5-6 month reviews with a haematologist, with a FBC a week prior. My absolute lymphocytes values were 5.2K, 6.2K, 6.4K and then 12.2K, the last value was in the beginning of 2021. Five months later, in June '21, the value was 23.0K, so the growth in numbers was pretty well doubling every six months.
I was placed on a more frequent review, every 2-3 months, and was told I would need treatment before the end of the year 2021.
Now in June '21 the Delta strain of covid arrived in Australia, and after advice from a medical practitioner I started in July with weekly doses of Ivermectin as a prophylaxis, the dose was 0.2 mg per kg bodyweight. I took this for about two months, and then increased the IVM dose to twice per week.
My blood test in early September showed that the lymphocytes had gone up to 27.1K, and I was still told I would need treatment in 2021.
My next blood test was mid November 2021, and the lymphocyte were 27.6K, followed by an end January blood test where the value was 26.0K.
I realise it's hard to draw a conclusion from a small number of data points, but the exponential growth of lymphocytes has stopped and reversed a tiny bit. More importantly, the haematologist keeps deferring chemotherapy, something I am not looking forward to, so I'm thankful for that.
Please don't take my post in the wrong context, I'm just posting a "me too" and in no way advocating that this is a treatment. I don't do politics and am just reporting facts from my body.
Note that my white cell count has followed a similar path as the lymphocytes, probably because they are related in some way.
I'm scheduled for the next visit to the haematologist at the end of March, and I'm very curious as to whether the downward trend continues.
My lymphocyte count continued to decline over time, and I didn't have any adverse effects from CLL except for the occasional night sweat and some weight loss. But the haematologist decided to start me on obinutuzumab and venatoclax 9 weeks ago anyway, and so far its been successful, the swollen lymph nodes in my face and neck have mainly disappeared. My blood counts are almost back to normal already.
I did test positive for Covid twice, once six weeks before treatment and once in week two of treatment, but both times the symptoms were very mild, and given that my immune system was not good that is something I'm thankful for.
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