Posting results of vaccine Covid antibody #’s - CLL Support

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Posting results of vaccine Covid antibody #’s

Yuck profile image
Yuck
12 Replies

Hi all,

Are people with CLL who take Ibrutinib or other BTK’s creating any Covid antibodies from the vaccines?

Many thanks!

Yuck

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Yuck profile image
Yuck
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12 Replies
Davidcara profile image
Davidcara

Not many that I have seen. Have seen people post antibody production, who are not on treatment.

Yuck profile image
Yuck in reply to Davidcara

I agree. Hoping for some posts showing that those on Ibrutinib made some antibodies from their vaccine.

Thanks!

jimvan profile image
jimvan

After reading the NY Times article today on Covid vaccine antibodies in immunocompromised individuals (nytimes.com/2021/04/15/heal... which specifically mentions ibrutinib as a stop to antibody production from the vaccines, I contacted my physician and requested a lab referral for a spike protein antibody test with numbers if possible, but I haven't heard back yet. I'll report the results if I can get a test.

KLWC profile image
KLWC in reply to jimvan

Is there any data about antibody production and those on venetoclax?

thompsonellen profile image
thompsonellen

Yes, I did and I am actively on ibrutinib, so it is possible.

Yuck profile image
Yuck in reply to thompsonellen

Thank you!

Artist123 profile image
Artist123

I'm getting my antibody test on the 27th of April. I've been on Ibrutinib for 9 months. I had the Pfizer vaccine (both doses) and waiting one month (thereabouts) after 2nd shot to get antibody test. Will post here once I get results. Don't have very high hopes, but it will be interesting nonetheless. Either way, I most definitely will continue being careful and smart when I'm out and about as I have this past year

Yuck profile image
Yuck in reply to Artist123

Thank you!

kimiD profile image
kimiD

I had my test through the LLS and the results were a disappointing <0.40. Initially treated with ibrutinib for 2.5 years and calquence for the last 2 years. I was hoping for a better response, but sadly not in the cards for me.

Yuck profile image
Yuck in reply to kimiD

Hi Kimi,

It is not you. BTK’s and CD20

are not friends of the vaccines. Once the monoclonal antibodies are readily available, the European world should also be ready for the onslaught of vaccinated visitors and those protected with antibodies. That will be something!

Stay safe and thanks for posting!

Looking forward to hearing from others on this topic.

~ Yuck

Bikram21 profile image
Bikram21

My brother is on Ibrutinib and he did produce antibodies. 🙏

Doggoneit101 profile image
Doggoneit101

Just got finished with Venteclax and apparently I have 0 antibodies.

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