Vaccines

[Davidcara]

Would appreciate thoughts: On ibrutinib, thinking about asking MD for Shingrix vaccination. I see second Shingrix vaccine should be given 2 to 6 months after 1st vaccine. Wondering if it is advantageous to take 2nd dose closer to 2 months or 6 months after 1st vaccine.

Also, wondering if there is a problem taking multiple types of vaccines close to each other. For example, flu vaccine followed by Shingrix a few weeks afterwards.

Am also concerned if this is the case, and coronavirus vaccine becomes available, will it be a problem if I am in the middle of Shingrix series.

[Mprm]

My hematologist recommended the Shingrix vaccine, though it was in the year before I began Ibrutinib and when my blood numbers were at their worst. Reaction to the first injection was a sore arm. I called for the second injection at 6 months and there was a shortage, so ended up getting the second at around 10 months after which the manufacturer was saying would still work (though I found the change of tune to be a little troubling).I had a more severe reaction to the second, with a fever and body aches, but was told this was good because my body was reacting. Definitely better than getting shingles! Though I guess you can still get a case, just less severe. I would definitely consult your hematologist about timing of vaccines. Mine encourages his patients to stay up to date on all non-live vaccines.

[Davidcara in reply to Mprm]

Thanks Mprm

[lankisterguy Volunteer]

Hi Davidcara,

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You are asking some complex questions that I doubt the CDC and Dr. Fauci could answer, but there is someone that may be able to help. You can use this link to pose your questions to Dr. Susan LeClair cllsociety.org/news-2/ask-t...

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Here are links to two CLL Society educational seminars where she talks about the reaction of a typical immune system to a vaccine:

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The first is this video from March 27 on CLL Society at time stamp 12:50 healthunlocked.com/api/redi...

see the graph shown.

And a later more text like explanation in a June 18 recording at time stamp 43.20 to 44:30 and 44:40 on healthunlocked.com/api/redi...

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What Dr. LeClair says is that a response to a viral infection or vaccine will cause a short lived IgM response producing antibodies 3-5 days after symptoms begin that may last for 30 days, and then a longer lasting IgG response to produce antibodies starting 10-14 days after symptoms.

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Len

[Davidcara in reply to lankisterguy]

Thanks lankisterguy, I watched the video and sent the email off

[KatieBlue]

I was given conflicting information.

First told it was very important to be on the day they scheduled the follow up dose, or for sure within 6 mos. That 2nd appt was right around 6 or 8 weeks after the first.

Then I had a conflicting appt due to a kidney stone and asked whether to go to the specialist appt or the 2nd Shingrex shot. I was told to go to the specialist appt for the kidney stone. That timing wasn’t critical for the second shingrex shot — as long as I got it within a year of the first.

Then enter covid.

I did ask if in May if they would be giving any vaccines curbside and was told that I could come into the clinic for the second one.

But I am not at this point or prior point comfortable with that and our numbers have only gotten worse to the point we have been described lately as the covid epicenter.