Hi. I have been treated with Ibrutinib, 2 years and 5 months ago, it has been going well for me. but I have palpitations and before starting ibrutinib I had a mild heart attack. These palpitations began to treat me with amiodorone, in small doses, but it brings ugly consequences for my thyroid. I am in a dilemma if palpitations are reduced under the dose of ibrutinib, but my nodes swell, if I continue with amiodorone, the thyroid is complicated, the liver is complicated. I live in Argentina . Has it happened to anyone? How do they cope? Thanks
ibrutinib and palpitations: Hi. I have been... - CLL Support
Hi Bixilon. I have heard some people report that if their doctor switches them to acalabrutinib instead of ibrutinib, the heart problems go away. Is that an option for you? Perhaps you could discuss with your doctor. Acalabrutinib is the next-generation version of ibrutinib and reportedly has less "off target" effects.
I believe the other option is a smaller dose. Heart issues are one of the side effects of this drug.
Sorry to hear that. I already have afib and racing heart and I am on verapamil for BP which heightens the effects of imbruvica. This is day 3 for me - so far so good but I think it the cumulative effect of the drug is when some of the riskier side effects kick in. I am concerned about this myself. Best wishes for your search.
This link is for an excellent booklet by the Leukemia and Lymphoma society in the states. (lls.org) it gives the various treatment options for cll. you can also email or live chat with them online as well.