Mushroom coffee

[Reeseru]

Has anyone ever try mushroom coffee? I am on Imbruvica,I just try it ,it's supposed to be all natural,your thoughts?😊

[AussieNeil Partner Administrator]

It's probably fine, but without information on the ingredients, impossible to say. Whether or not something is all natural is not the issue, it's how it can potentially interact with medications that matters. This is why we shouldn't have grapefruit and Seville oranges (think juices, marmalades), when taking Imbruvica (ibrutinib) and many other medications, as they can worsen side effects.

Added: We need to consider 'All natural' as a marketing phrase. It's not the same as 'safe to eat, drink or apply'. Think acids, poison ivy, etc.

healthunlocked.com/cllsuppo... Neil

[Skyshark in reply to AussieNeil]

The issue with Grapefruit and the other CYP3A inhibitors is that they inhibit production of the enzyme CYP3A. CYP3A metabolises Venetoclax and all cBTKi drugs. When CYP3A is inhibited the blood concentration of the drug increases.

St John's Wort (Europe?) a common over the counter health supplement is an inducer of CYP3A and must also be avoided as that will reduce the blood concentration and would require an unquantified higher dose to compensate. That could only be found by testing blood for drug concentration - something that is only done in phase 1 trials.

Again for Europe Belladonna, Deadly Nightshade is "all natural".

[InFlorida]

IMHO: all natural means nothing. To me, if it’s not proven, I don’t take it/want it. I don’t understand why people take things that aren’t medically approved / tested akin to “howling at the moon” 😉.

[Oleboyredw-uk]

Unfortunately ‘natural’ is all things to all people, especially marketeers. Grapefruit is ‘natural’ but sadly I’d not go near it intentionally (not literally).

However, what ‘natural’ would do is to encourage me to investigate the contents further as I prefer to have a more natural and balanced diet without the need of any supplements. While I’m on that subject I’d only take supplements if advised to do so by my GP and not some glossy advertising.

best to all, robin

[Reeseru in reply to Oleboyredw-uk]

😊😉thank you

[Milla15]

😱😱😱😱😱😱😱😱😱

[sdowney8600]

Also, I know one of the brands of mushroom coffee called Clevr Blends contained lead on its initial launch. Thankfully they got tested --which doesn't always happen--and the lead was found and they had to pull their product from the market and start over. Many of the "all natural" products are not tested or regulated like regular foods and don't go through the same testing regimens. And then you'll never know what kind of toxins are lurking in that innocent looking box.

[Reeseru in reply to sdowney8600]

Thank you 😊

[Mango357]

If you would like to try mushroom coffee it's better to buy the coffee beans of your choice & your own dry whole mushrooms so you know exactly what you are consuming. I am partial to Blue Mountain & Kona coffee but they are expensive. I am currently trying Turkish coffee. Each bean has their own benefits. Mushrooms can be expensive too depending on which one you are buying & where you are buying it from. An excellent or very good local Chinese or Japanese grocery store is usually best price wise. Nuts.com is known for quality across the board but they are not cheap. If you have a Vitamix or a nut grinder, grind a small portion of the beans as course or fine as you wish. Grind the dry mushroom separately. Add a little of the ground mushrooms like a level quarter teaspoon or less to your coffee grinds before pouring hot water over it. This way you can add the mushroom of your choice on any given day & see how well your system handles it. If it works well for you then you can do combinations specific to your needs or comorbities. You can also sprinkle a little finely powdered mushrooms into green tea lattes, tumeric golden milk, dark or black chocolate (decadent), homemade salad dressing or just sprinkle directly into food. Do not mix medicinal herbs with prescriptions. Wait 2-3 hours or so between medicinals & prescriptions. Research scientific sources for benefits & contraindications if you have not done so already. Memorial Sloan Kettering, a well known cancer hospital has an extensive public herbal database from their integrative medicine webpage. It lists many different mushrooms with their properties & side effects. Talk to your physician & pharmacist. Accurate knowledge is power. It helps us make good decisions to lead our best life despite trials & tribulations. All the best to you in whatever you decide to do.

mskcc.org/cancer-care/diagn...

[Reeseru in reply to Mango357]

Thank you for that advice!🙏

[DanBro1]

Don't know much about mushroom coffee, but I do pop a couple of Lion's Mane each day.....

[Reeseru in reply to DanBro1]

😉😉, thank you! It has Lion's mane in it,😉😀

[WinJ3]

I’ve been drinking a brand called Microingredients Organic Mushroom Coffee for over five years now, and I’ve had no issues with it. In fact, my lab results have improved slightly, and I definitely feel more energized. I’ve always loved coffee, but I wanted to cut back on caffeine—one big benefit of mushroom coffee is that it contains less caffeine than regular coffee. Plus, mushrooms themselves offer a variety of health benefits.

That said, mushroom coffee does take some getting used to. I experimented with different creamers—almond, soy, coconut, hazelnut, vanilla—you name it, until I found the one that tasted best for me. Taste is personal, so it may take some trial and error.

Just to be clear, I’m not a medical professional, and I don’t claim any authority on the health benefits or safety of mushrooms or coffee products. I have no proof that mushroom coffee or mushrooms helped my labs or energy level. This is simply my personal experience. Always check with your doctor before trying anything new.

[Reeseru in reply to WinJ3]

Thank you 😊

[AussieNeil Partner Administrator]

A general warning about mushrooms and CLL. The B cell receptors on IGHV mutated CLL cells are not random as one would expect, but have a property known as stereotypy. They show a preponderance to selectivity towards specific epitopes, which for unknown reasons are often fungal in nature. One CLL research study into stereotypy, determined that a fraction of a percent of us have CLL which is stimulated by exposure to fungal beta glucans - the protein used to make fungal cell walls. One member noted that her CLL turned aggressive when she started using a mushroom supplement to hopefully improve her immunity. She shared that she considered that trying the supplement hastened her time to starting treatment.

More importantly, if you look into the evidence provided by manufacturers claiming a supplement boosts immunity, you'll usually find that the cited study shows evidence of increased lymphocyte activity and division in subjects taking the supplement. For this reason, I recommend against taking anything claiming to boost immunity unless you carefully check the science behind it. I'd also recommend keeping an eye out for changes in lymphocyte count trends if you decide to take the supplement.

Neil

[Reeseru in reply to AussieNeil]

You don't have to tell me but once, I only took 4 cups mushroom coffee,in two days hopefully it a get out of my system,when I go to the doctor in June. Thank you Neil!🙏☺️

[AussieNeil Partner Administrator in reply to Reeseru]

Here's the paper: A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi

In this study, we describe a new subset of M-CLL, expressing stereotypic BCRs highly specific for β-(1,6)-glucan, a major antigenic determinant of yeasts and filamentous fungi.

pubmed.ncbi.nlm.nih.gov/232...

along with the commentary, with my emphasis: Clonal expansion in B-CLL: Fungal drivers or self-service?

First, recombinant soluble IgM from these cells bound to 4 commensal yeast species (out of a total of 33 microbial species screened) and showed high-affinity binding to B-(1,6)-glucan.

Site-directed mutation experiments de­mo­nstrated that reactivity was dependent on a glutamic acid at position 106 in the CDR3 region and on additional somatic mutations in IGHV3-7. Second, CLL cells from three patients proliferated in response to the B-(1,6)-glucan pustulan. Other mB-CLL cells and other recombinant BCRs did not show this specificity.

pubmed.ncbi.nlm.nih.gov/233...

As I said, it seems to be pretty rare, but something to keep in mind, particularly if you know you have IGHV mutated CLL.

Neil

[CLLBGone]

I prefer my mushrooms at a hip music fest with slamming bands on a sunny day.

[Reeseru in reply to CLLBGone]

☺️☺️