Hi, l need some advise.
I was diagnosed 6 years ago with CLL. I have been in W&W until recently my hemoglobin decreased to 10.2. I also have some enlarged lymphnodes but it doesn’t bother me.
Dr. believes that this is the time to start treatment soon. Dr Wierda at Md Anderson recommended me to contact Dana Farber as my last blood test came up that I have 17p deletion and they currently don’t have any clinical trial for me.
Dr Wierda recommended me the clinical trial on Acalabrutinib, Venetoclax and Gazyva. I also on my own found out that they have another clinical trial with just one drug: Zanabrutinib.
I don’t really know what to do, but most of the time I feel that the combination of 3 drugs will be more toxic and probably with more side effects, which I am so afraid of and I know it was what Dr Wierda recommended but I want hear your experience with theses combinations and also your thoughts with Zanabrutinib only.