71yr male diagnosed 2yrs ago, CLL (Binet stage B) researched specialists and decided on Dr Bloor at Christie Hospital in Manchester, an excellent choice. W&W for 18 months until he found a mass of raised lymph nodes in my abdomen. Dr Bloor suggested the Flair trial and I was randomised for FCR beginning mid Oct.
My HDMS sample showed a typical CLL phenotype with germline IgVH and trisomy 12
I believe this means my likely remission after the FCR is reduced to approx 2/3 yrs.
Have now had three monthly treatments, the next is due 10/1/18. Side effects so far have been minimal, felt rough on days 4/5 after the first dose, less so after the second dose and ok after dose three. I had a change of anti sickness tablets last time to ondanestron, which I took twice a day for the 5 day treatment period, Hopefully this is the reason I felt okay. Previously I had a single Akynzeo tablet before starting the Rituximab infusion and a supply of Metoclopramide to take if needed.
I had a rash on my body after the first round, the Co- Trimoxazole anti-biotic tablets were replaced by Pentamidine 300 mg via nebuliser for rounds 2&3. I also take 800 mg of Aciclovir every day
Will update this post after my next treatment