74 y.o. w/f patient who In 2013 officially dx'd , wbc's elevated, oncologist said w/w for a while as asymptomatic, then in 2014 count .100,000 he said I had to do something so got Treanda - felt lousy with it, had two cycles, then next month Treanda with Rituxin, became totally neutropenic, in hospital for 3+ weeks. No treatment except Prednisone for two years until 2015, MD tried Ibrutinib 140mg, one tablet every day,became nauseated, lost my voice after 1 pill, med d/c'd. In April of 2016 MD and I decided to try Ibrutinib again at one tablet per day. After about 4 days, my left hand swelled up lto the size of a boxing glove, looked like cellulitis.Was on med 7 days. Admitted to Hospital for 9 days, blood cultures negative, massive IV steroids and abx. Resolved. Went to see Dr. Jennifer Brown at Dana Farber in August 2016. No further treatment until November 2016. She recommended an IV chemo drug or possibly Venetoclax, neither of which I was anxious to take. My local MD and I decided to try Ibrutinib at one tab every three days. . At that time my MD said I was dying of CLL .Counts repidly declined, two weeks ago we stopped med due to pain and swelling in both legs, mainly ankles. In February, noticed hearing loss in one ear, not some in other as well. Total workup by ENT MD. Now I have pneumonia but starting to recover. See MD Monday, for labs. Lymph nodes very small axillary, none else where.