First off, be assured that although I post rarely, I do regularly read and digest the all the posts here. I have benefited from the wealth of knowledge found within the threads.
Much as I would like to indulge in relating the nitty gritty of my new talking points. I will restrain myself and try to stick to the bullet points.
* 6 rounds of FCR in 2014 with continuing good CLL partial remission. After 6 months of monthly consultation, my 2 recent consultations have been 3monthly.
* Last evening I had an; not too unpleasant, Endoscope appointment quickly followed by an Endsocopy Report.
1) Hiatus hernia (It's alright, I can live with that but, it will be hard for me to keep a conversation about it going, for a boring hour or so)
2) Barrett's Oesophagus, now that's a different kettle of fish (imagine the hours I could ramble on about that!)
My gastro consultant, much like my hemo consultant on my first visit, was quick to point out that, although not pre-cancerous I'd probably die of something else before my Barrett's turned bad. (I've the good flavour of leukaemia and best case Barrett's)
Hidden within Dr Google's world of doom and gloom, I stumbled upon the comfortingsnippet below from ncbi.nlm.nih.gov/pubmed/980...
However more interestingly, delving deeper I discovered that Barrett's has an association with B cells.
I have yet to meet my hemo consultant (next month) to discuss this development and do not intend to live in fear or trepidation either now or after my meeting with her.
My query simply is - Has any of the CLL'ers here, had an acquaintance with Barrett's Oesophagus?
Rapid progression of Barrett's esophagus to metastatic esophageal carcinoma in a patient with chronic lymphocytic leukemia.
Hsu CW1, Krevsky B, Sigman LM, Thomas RM.
Barrett's esophagus is a common premalignant condition that predisposes to the development of adenocarcinoma of the esophagus through a process of transformation from metaplasia to dysplasia and then carcinoma. Periodic endoscopic surveillance with multiple biopsies is adopted by most physicians to detect dysplasia or early carcinoma. We report a case of an 80-year-old white man with chronic lymphocytic leukemia (CLL) who had periodic endoscopic surveillance without any evidence of dysplasia or cancer, and who died of metastatic carcinoma of the esophagus only 18 months after his last upper endoscopic examination. We suspect that the relative immunosuppressed state resulting from his CLL was the major contributor to the rapid progression of the Barrett's esophagus to cancer. Patients with CLL have higher risk of second cancers, and several cases of aggressive carcinomas have been reported in association with CLL. This is the first case report of metastatic esophageal cancer arising in Barrett's esophagus in a patient with CLL. This case suggests that we might need a more aggressive surveillance strategy for Barrett's esophagus in patients with CLL or other immunocompromised conditions.