I am starting my 3rd month of imbruvica and up until now it has been going great. They called yesterday after my bloodwork and my liver enzymes are elevated. from 19 to 134 and 15 to 211. Up until yesterday my liver enzymes have been normal. I have not been sick in any way. My local oncologist thought it may be related to the imbruvica and is having me hold the Imbruvica for 1 week and retest my bloodwork at that time. Has anyone experienced Imbruvica interfering with their liver enzymes or have any clue why my enzymes would be elevated???? Is it wise to stop the Imbruvica? Thank you so much for reading and giving me some knowledge.