Diffuse Large B Cell Lymphomas are aggressive lymphomas that those of us with CLL face a chance of developing in what is termed Richter's Transformation. Given the risk increases the longer we live with CLL and at between 5 and 15% is not insignificant, if you notice any bumps quickly growing, get them checked out promptly.
In this very technical blog, Dr Sharman explains how the two main DLBCL subtypes are identified and how this influences treatment.
He also provides some interesting information on the wide difference in treatment response observed with lenalidomide and ibrutinib drugs when treating the two main DBLC subtypes and concludes "I think we are getting really close to making some important steps forward in the management of DLBCL-NOS and it will be driven by molecular information that leads to targeted therapies that are specific to the patient."
These cockatoos were enjoying munching on some pine cones when I interrupted their feeding. I subsequently 'captured' them keeping a watchful eye on me after they relocated to a safe perch in a nearby eucalyptus (gum) tree.