I started FCR in March this year and have just had my second treatment. I didn't react too well to the first treatment - only half the Rituximab was given, I was too unwell on day two to continue. I was shaking, experiencing tingling in hands, weakness, vomiting violently and have uncontrollable diarohhea. Blood tests showed my sodium level was low and I was admitted to hospital, given IV fluids, stronger anti sickness and an anti diarrohea medication. I was discharged 3 days later.
I have just had my second course as an inpatient, the Rituximab was given again over 2 days with the F and C starting on day two. My F dose was reduced by half. I seemed to be doing OK and was discharged on day 4, but on day 5 of the F & C I again started getting diarrohea and nausea, loss of appetite, weakness. Again I was admitted with low sodium, by which time I was vomitting violently and shaking uncontrollably for around 3/4 hours.
After IV fluids I started to recover, my sodiium level improved and home I went. I have maintained improvement, just very tired and I guess a bit pathetic.
I have a consultation in a couple of weeks to discuss where we go from here. My lympocyte count is in now in the normal range and my enlarged lymphs have melted away, and a spleen tip has gone.
Any thoughts gratefully received!