I was diagnosed with Lupus in Jan2013 and to cut a long story short was put on Methotrexate -was on if for 8mths (I will add at this point that I am totally TEE-TOTAL and have been for about 9/10yrs) - then got an Urgent call from my Rhuemy to STOP immediately, as Liver readings were very high (I had done exactly as Rhuemy asked and had EVERY blood test I was told to!!!)-then been on steroids and different meds for Lupus - around Jan 2014 was feeling really unwell and GP examined me and referred me for a Liver scan,as he said my liver was enlarged - finally saw a Heptologist at same hosp as my Rhuemy-they said there was scarring BUT that it was quite steady-not getting any worse-was probably related to my immune system and did not need any treatment (the letter mentioned smooth cells-which I looked up and can indicate AIH)-and that I did not need to go back as they would monitor me with blood tests through my Rhuemy-I started a new drug for my Lupus that I had sourced myself (LDN) and was doing brilliantly-then about 4 weeks ago I got bitten/stung during the night (not sure by what!!) and my leg really came up bad- I had to go to the walk in centre at local hospital where I was given a really high dose of Antibiotics-one lot of 500mg 4xdaily-and a different lot of 500mg 3xdaily (I had told the nurse about my liver/lupus)-half way through the course I could feel my Lupus rising - then got thrush and was given another antifungal/antibiotic- By last weekend I felt just SO ill (I thought it was a LUPUS flare) could not go to work-on the Monday I had a blood test for my upcoming Rhuemy appt (in August) went back to work last Saturday( I work weekends) and had to be sent home-when I got home there was a letter from the Rhuemy saying that my Liver Enzymes are really high again.....Went to my GP this Monday and have been signed off for 2 weeks- am still feeling really rough-hot sweats-heart racing-joints aching-hard to go to the toilet and wee really dark-feeling nauseous and not at all hungry...And I know that it was the high dose of Antibiotics that set it off, plus, I had taken painkillers for my (what I thought) Lupus flare-which causes aches and pains-WHY did the Heptologist not warn me about painkillers/antibiotics??? Am just so ANGRY!!! I am now really worried that my liver is damaged to the point that it won't heal, and feeling really let down by the NHS-my GP (who is good) is now writing to the Heptology dept to find out what to do next-but they had not even bothered to tell him that they were going to monitor me through the Rhuemy-he has heard nothing. AM VERY ANGRY!