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Breast Cancer India
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Hormonal therapy in secondary breast cancer

My mom intially diagnosed with Breast cancer in 2011 august, we done surgery at that time and had 6 doses of chemo. After that she had a recurrence(Jan 2017) in same area and we did a PET scan which showed lytic lesion in 2nd and 4th ribs(Max Suv - 4.2), and uptake in left sterni manubrium(suv -3), So went for 30 doses of 3DRT radiation to chest wall and 4 mild doses of chemotherapy.Again we took a PET scan(July 2017) for response assessment which showed results as there is uptake only in left sterni manubrium(max suv -6). As she is ER/PR+ and HER- our oncologist suggested for Hormonal therapy. So for the past two years she was under hormonal therapy and every blood test , xray and usg came fine. Last week (May 10,2018) we went for a PET scan which showed results as " No metabolically active disease present anywhere in whole body survey). I am posting both of pet scan impressions below.

PET SCAN Impression(July 06, 2017) :

Intensely hypermetabolic screlotic lesions in manibrium sterni on the left side(Suv of Max 6) and there is an interval resolution in rib uptake. No definite evidence of metabolically active disease anywhere in whole body survey.

PET SCAN Impression(May 10, 2018)

Skeletal Area :

No Pathological focus of FDG uptake noted in extremities and musculo-skeletal area

Ametabolic Screlotic lesion noted in manibrium sterni on the left side

Final Impression :

No definite evidence of metabolically active disease anywhere in whole body survey

There is an Interval resolution of metabolism in sternum uptake.Suggesting complete metabolic response to therapy.

Still she was under hormonal therapy only and getting zoldrenic acid every 3 months and she is doing very well. Please help me with below queries

1.Do we need to undergo any test to check whether the hormonal status is changed?

2. For how many years we can continue hormonal therapy, do we need to change the medicine(now she is taking femara)

I am bit worried, as i wanted to make sure that i wanted to provde all the possible treatments for my welfare and health

3 Replies
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No need to check now as it is evident that hormone therapy has worked. From the PET findings.

No need to change medicine since we know the present one is working. We change only when it does not work.

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Many thanks for your support sir.can you pls tell for how many years hormonal therapy will be beneficial sir.. also sometimes she is getting tingling pain sensation in abdomen area and it goes off,,we did a ultrasound for abdomen and everything is fine,,she is taking tablets for diabetes, will it be the reason sir

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Your story provides me with hope, as my mother is undergoing similar issue.

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