Just wondering if anyone has found remission with depression and anxiety. I crashed (breakdown) 4 weeks ago. All job related and not taking care of me. I feel like I have adrenaline going off all of the time.. chest tightness, insomnia, and depression. I started Zoloft titrated to 75mg and and Trazadone 150mg could not tolerate. Unable to sleep, 3 to 4 hours on Trazadone with muscle twitching and jerking. Now reduced Zoloft considering switching to Lexapro, added 25mg of Seroquel for insomnia. I do not like the Seroquel but I am sleeping. Looking for hope here, its been 4 weeks going on 5.