Over a three week period, my PSA went from 303.0 to 465.0; indicating a doubling time of 32 days. After failing Keytruda after 3 rounds, my MO gave me three options: (1) Try a doublet therapy with atezolizumab infusion along with the oral medication cabozantinib, (2) start Jevtana or (3) keep me comfortable and I guess let me die. My MO pointed out that docetaxel is a taxane-based chemotherapy like Jevtana. I was already aware of this and the numerous side effects I encountered while on docetaxel. The first option sounded intriguing. I had not heard of these meds used for prostate cancer. That is the option I chose. My medical insurance denied both meds. After a peer-to-peer meeting between my MO and my insurance, the infused med, atezolizumab was approved. I start that infusion on 29 November. My insurance has been pushing back on approving the oral med. I was told I could file a grievance with the State of California's managed health care department. Luckily, my medical team at Stanford is handling that. It’s getting overwhelming dealing with all of this on my own. But, I’m not ready to go! Attached is my new tattoo that was completed one week ago. There is a lot of symbolism of a blue dragon and cherry blossoms or sakura in Japanese.
I am curious if anyone has taken these 2 meds and what information can be shared.
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MJCA
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Yep. When I was told what I needed to do I flipped out. Luckily, Stanford is dealing with it. You must be familiar with the drugs - what’s your opinion? As always thanks Allen!!
You can check out the webinar recording "November 18, 2024: Immunotherapy for Prostate Cancer: What’s Now, What’s Next". In this webinar, round 34:00 mark, Prof Agarwal who is the principal investigator of this clinical trial from University of Utah discussed about the outcome of this trial.
Hope this info will help you get a better understanding of the trial and how it may help you.
Hi Mark. I hope the combo will work for you. If not, oncolytic viruses such as NDV (Newcastle disease virus) can lead to partial/complete remission in very rare cases.
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Three clinical trial options after Zytiga fails
Given another 18 months of life if continue treatment. Starting cabazitaxel this week. Side effects?
Triple Therapy
Stopping docetaxel at just 4 per Dr - good move or not?
FOR46 Trial - How the heck to decide? 
