After 14 weeks on Zytiga, PSA has gone up over 100 points, to 250, and pain is worse in back, hips and pelvis. Failed Xtandi quickly too. Ex asked about discontinuing treatments and ONC gave him a 6 month prognosis. He reluctantly decided on Jevtana and external beam radiation even though he had a difficult time with docetaxel. Anyone have more side effects with cabazitaxel than with docetaxel? We are not that thrilled with Jevtana as his PSA only climbed and bone mets got worse while on docetaxel. (Diagnosed 16 months ago, PSA 2739, hundreds of bone mets, bone marrow metastasis, age 44).