Experiences with

Atezolizumab

Atezolizumab (Tecentriq) will shortly be assessed by the Scottish Medicines Consortium (SMC) for use in NHSScotland, and we have been invited to provide a Patient Group Submission for the medicine. We are therefore trying to gather some patient experience quotes.

Hi everyone, Dad has been informed he may be potentially eligible for a trial involving cabozantinib and atezolizumab. Has anybody had any dealings with this and if so, did it seem effective? Many thanks as always!

Mum didn’t really get the chance to ask any questions but is continuing on the immunotherapy therapy trial drug of Atezolizumab A stupid question maybe but does the fact that the lymph nodes are now of a normal size mean that the cancer has been zapped up?

Mums continuing on the trial drug of Atezolizumab. Had her dose of the trial drug only this week. Had a few symptoms but is starting to feel better. It’s a two year trial. Would love to hear from someone who can hold my hand xxxx Love and best wishes to you all xxxxx

The immunotherapy drug atezolizumab also won FDA approval in May 2020 for improvement in survival over standard chemotherapy for many patients with newly diagnosed NSCLC, based on research from Yale Cancer Center and Smilow Cancer Hospital.

First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer. N Engl J Med 2018;379:2220-9. [Crossref] [PubMed] Paz-Ares L, Dvorkin M, Chen Y, et al.

Does anyone have experience that they can share with an immunotherapy called Atezolizumab please? I start this as my next treatment option next week. Wishing you all my best.

The consultant advice me to use the new drug atezolizumab. After being told that I have 6 months to live I have been able to live a normal life for 2 years and 5 months. It is harmless and very minor side effects if any. I hope more people could receive this wonderful creation

We've been offered two options: 1. a trial of atezolizumab + cabozantinib - an immunotherapy treatment that seems to be promising in Breast Cancer. But, if he is put into the control group, he'd receive enzalutamide (another ADT drug). 2.

Anyone with advanced breast cancer er/pr+, her2 neg, asked to do this trial? I am a bit concerned because I was dx with luminal A in 2016 and had a lumpdectumyin left breast. Found lymphnodes too. Had 12 rounds of chemo and 18 days of rads. Was on anastrozle until Dec of 2019 with progression, mets.

Atezolizumab is a monoclonal antibody that was approved by the US Food and Drug Administration in 2020 for the first-line treatment of adult patients with metastatic NSCLC. https://www.iaslc.org/iaslc-news/press-release/lcmc3-neoadjuvant-atezolizumab-safe-meets-primary-endpoint-pathologic

The plan and probably my last chance is for Atezolizumab immunotherapy which I start next week. I thought it would be Keytruda but he said the above was better for my circumstances. Does anyone have any positive results to the above treatment please or experience of having this drug.

Oddly, for such an aggressive cancer, it actually has a low mutational burden which explains why the atezolizumab didn't work. As I understand it, my cancer isn't different enough from my healthy tissue for my immune system to care.

I’ve been on a clinical trial of a combo of Cabozantinib and Atezolizumab for three months now. It’s a combination of pill and infusion. My Mets that involve my lungs, liver and lymph nodes are staying in check. But my PSA climbs 20 spots every three weeks of my treatment.

My body has been beat up by 9 cycles of chemotherapy so far this year, not to mention atezolizumab which faield. I really was hoping for some form of remission to allow my body to recover and get healthy again before having to continue the fight.

The Mayo Clinic has accepted me to get either cabozantinib (XL184) alone or in combination with atezolizumab (immunotherapy). Cabozantinib is an oral agent which is great and is FDA approved for medullary thyroid cancer. This is a phase 2 study.

In other news, I completed chemo back in June, finished radiation in July, and continue on Atezolizumab, Lupron, Abiraterone, and Xgeva. I'm finally beginning to see glimpses of improving health as I recover from the chemo and radiation.

Atezolizumab - Vemurafinib - Cobimetinib. Ryan did not fair well on a dual therapy, so I’m not sure if that will be the course of action. Definitely has to be discussed. Once the bowel heals and functions correctly he will be able to eat without restrictions and go back to normal life.

This study will compare the effects, good or bad, of atezolizumab plus bevacizumab versus active surveillance (not receiving any study treatment) on patients with completely resected or ablated HCC who are at high risk for disease recurrence Patients will be put into two groups or Arms of the study:

I had 12 consecutive weeks of Ptaxil, Carboplatin and either a placebo or Atezolizumab (pretty sure it's the Atezolizumab). I just started my 4 dose - 2nd round of Doxorubicin, Cyclophosphamide and placebo/atezolizumab 2 weeks ago....Lord, that was a rough ride for 7 days after!