Experiences with

Jevtana

Hello, As promised, I’m opening a thread to chronicle my experience with Jevtana/Cabazitaxel. My first treatment was yesterday, 3/26/2025, and so far, I can report a mostly eventless 24 hours.

After Jevtana and Pluvicto fail, recommendation was to start Xofigo but his hemoglobin level is currently low at 7.8-8.0 Anyone have any success switching to other ADT type therapies in the meantime?

(as second chemo) https://www.prostatecancer.news/2020/05/lu-177-psma-617-vs-jevtana-cabazitaxel.html • Survival is improved by combining Pluvicto with Xtandi vs Xtandi alone https://www.prostatecancer.news/2024/04/pluvictoxtandi-delays-progression.html Sequencing does not seem to matter very much

After the 5th Jevtana infusion, my husband’s blood sugar was found to be in the 170s. Duke notified him to see a doctor. He has diligently been restricting carbs and sugar but his numbers are still high. Anyone else encounter this? Thanks!

Prior to pluvicto, my father did 4 rounds of Jevtana but that also did not make much of a dent. Doctor is recommending Xofigo at this point given most of my fathers metastasis is in the bone but looking ahead what other treatment options should we be considering? clinical trials?

After a lengthy discussion, we decided to start Jevtana and possibly Xofigo along with still taking the Orgovyx. After reading many posts on here (thank you everyone), I don't think I've seen one positive post related to either Jevtana or Xofigo.

My MO and I discussed Jevtana which sounds like the end of the line. I am asking those who have had Jevtana, how bad are the S/E in comparison to docetaxel. I know both treatments are taxane based, so I would expect similar side effects. Thanks for your assistance.

After failing Keytruda after 3 rounds, my MO gave me three options: (1) Try a doublet therapy with atezolizumab infusion along with the oral medication cabozantinib, (2) start Jevtana or (3) keep me comfortable and I guess let me die.

After failing Keytruda after 3 rounds, my MO gave me three options: (1) Try a doublet therapy with atezolizumab infusion along with the oral medication cabozantinib, (2) start Jevtana or (3) keep me comfortable and I guess let me die.

My husband and I are waiting for his first Jevtana infusion. We learned today that his PSA jumped from 1.9 a month ago to 3.55 today (not had a high jump like that maybe ever?). Also learned he is castrate resistant.

Thoughts on next steps; trial of taxotere/jevtana? I'm assuming switching ARI will likely not have a huge effect as it's all same/similar mechanism of action for cancer that's castration resistant now...? Pluvicto (if even possible to get)...provenge?

Hello all, I have been hearing Jevtana has less side effects than Docetaxel. My husband seems to be having a harder time, he has nausea he didn’t have before and some serious insomnia. Tough to deal with while working FT.

Would appreciate any information for Jevtana treatment. At doctor's appt yesterday, my husband's hemoglobin had decreased to 7.6 and he had to have a blood transfusion. His Alkaline Phosphatase went up again. He will start on Jevtana on June 20th. We are hoping this will do him some good.

My PSA recently started climbing and is up to 30 now while on Jevtana and Carboplatin. What other treatments should I be asking about? Hormone therapy stopped working about a year ago after being on it for about 6 months. Taxotere worked well when I was on it a year ago.

Would appreciate any information for Jevtana treatment. At doctor's appt yesterday, my husband's hemoglobin had decreased to 7.6 and he had to have a blood transfusion. His Alkaline Phosphatase went up again. He will start on Jevtana on June 20th. We are hoping this will do him some good.

I started Jevtana and carboplatin about 9 weeks ago. I have what is described as" PSA surge". When I started my psa was 4.4 now 8.3. Has anyone else experienced this? What if any thing was done?. My Mo says stay the course, scans to be repeated in July. Thanks for all your help

I have noticed that some men on this site have had over 30 infusions of Jevtana. My husband has had completed 10 sessions of docetaxel. The last three were given with a second dose of Carboplatin. Jevtana is new to us. How is it tolerated? Why can it be given at such a high number of doses?

I finished cycle of Jevtana (7 infusions) and Xtandi. My PSA was 0.74, but now it has increased to 2.3. All other tretments and history are in my bio. The last Pet-choline done in Feb. 2024, did not show any mets, probably because at that time my PSA was 0.6.

Believe it or not I feel fine after receiving Jevtana and Carboplatin, its that shot of nuelasta thats killing me for 3 days.

Does anyone have experience with side effects from Jevtana )cabazitaxel) IV? I’m starting next week and just wondering how prevalent some of the classic effects are? Thanks!