Going on to Pluvarco

[Goldberg]

Carbotaxil + Doxitacil Did not work. Still had progression in the bones and Mets. MO ordered JEVTANA . Meanwhile I have just been notified that I possibly am a candidate for Lutitium trial. They have said to cancel the Jevtana infusion which I did. I am BRICA2. Any thoughts about the efficacy of Lutitium over Jevtana

[Tall_Allen]

Have you tried Lynparza yet? There is a trial in Australia now of combining Pluvicto and Lynparza:

clinicaltrials.gov/ct2/show...

Even if you can't get the combination, Lynparza is probably the best next choice.

Usually, Pluvicto is clearly a better next choice compared to Jevtana. But a recent analysis found that if a PSMA PET shows low avidity and an FDG PET shows high uptake, the choice isn't very clear. It is probably a good idea to get both PET scans:

meetings.asco.org/abstracts...

[Seasid in reply to Tall_Allen]

he is excluded. He already had Olaparib.

[Tall_Allen in reply to Seasid]

Thanks - nothing in his profile and I didn't bother to read all his previous posts. Is he in Australia?

[Seasid in reply to Tall_Allen]

i believe he must be in US but the best would be to state age, location and therapies.

at least we others have benefits from your answer.

maybe he could talk to professor Hofman and ask for exemption?

[Seasid in reply to Tall_Allen]

thanks for the clinical trial link in Sydney and Melbourne.

[Goldberg in reply to Tall_Allen]

I apologize for not including more info. I am BRCA2 have gone through zytega, xtandi, Radium 223, Lymparza, directed Radiation to my spine, and lastly carbotaxil + doxataxil after which has not stopped the increase in bone Mets and the size of lymph node Mets. I will be talking to UCSF about the Pluvaca trial. Jevana had been mentioned as a in between while I am waiting to to qualify for pluvaco They are also applying for a compassionate use exemption to use Keytruda if the other procedures do not work. All of which means to me I am Kind of heading to the last round up.

[Seasid]

it would be great if you could at least list all your treatments in your profile as lot of inclusion and exclusion criterias are based on them.

i wish you all the best.

István

[Seasid]

could you phone professor Hofman? Maybe he could make an exemption

[Janhpr]

I emailed Mike Hofmann re Lu 177 he told me the hospital he works at in Australia provides Lu free and he advocates PSMA and FDG scans routinely also I believe he is trials

[Benkaymel]

Hi Goldberg, as others have said, it would really help people to help you if you filled in your Bio with a basic treatment history rather than having to sift through all your previous posts.