Hi everyone. This would be my first post here, I am feeling stumped and lost and I'm not sure what to do. For context, dad has the BRCA positive mutation gene.
My dad (56) is experiencing a lot of bone pain for the past 4 weeks. He has been through Leuprolide acetate, Lu-177, Olaparib (Lynparza), Abiraterone (Zytiga), 5 rounds of Docetaxel, and brain radiotherapy due to meningeal metastases, as well as a ureteral stent placement procedure done due to a recurrent cancer mass where the prostatectomy surgery site was done.
His latest PSA levels in June was at 16 and latest PSMA PET Scan was on Dec 2023, the mets are mainly in the spine, femur, ribs, and hips.
He is now receiving Enzalutamide / Xtandi (just started 12 days ago) and I am not sure if it's the bone mets or the meds, but it has been so hard on him. He has lost 12+ kg in the last month, he sleeps his day away, and can't even walk in a straight line. I am so sad because he used to be so full of life, exploring the city with his bike, and now he is having a hard time even getting up from bed.
MO has led us to palliative care, but I feel like it's too soon and I am not trying hard enough to find another treatment that would work for him. For now, his urologist advised us to wait for a month (August) and check the PSA levels to see if the Xtandi is working any good.
I am not sure what to do anymore, he is in so much pain and is taking Ultracet (Tramadol + Paracetamol) 3 times daily and Celecoxib for anti-inflammatory effects. We had to go to the ER today as his 5mg Morphine tablet did not ease the pain at all and the ER doctors gave him bolus of Parecoxib which only lasted 6 hour.
Would it be possible if we get more radiotherapy treatments to ease his bone pain? Does anyone have any experience with receiving chemo again, is that even an option?
Hope you and your loved ones are doing well, any thoughts will be appreciated. Thank you so much everyone