degarelix v/s eligard "lupron" - Advanced Prostate...

Advanced Prostate Cancer

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degarelix v/s eligard "lupron"

yardsailor profile image
12 Replies

my baseline psa was1316 with a elevated alkaline phosphatase of 270 12/2021 , on 01/13/2021 my psa had risen to 1665 to avoid a further psa spike I was given a loading dose of 240 mg of degarelix followed by 80 mg every 28 days for 18months then for 3 mouths this last summer a three month dose of Eligard to allow for a long cruise .now that I am back home I decided to go back on degarelix with its 28 day cycle .With the help of aberaterone my psa has remained at.014for the last 10 months.My question is this wise to continue with degarelix I notice most of you brothers are getting lupron l as your first line adt therapy .My treatments are with a small local hospital,my mo is overseeing many types of cancer I do however go to boston once a year and see Dr Matthew Smith at Mass General HospitalCancer center for oversight of my treatments. So far he seems impressed with my care. I am trying to educate my self about this prostate cancer,my mo says if you find something , you think will help you, I will look into it I guess that is a good thing. Thanks for letting me go on and on.

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yardsailor
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12 Replies
Tall_Allen profile image
Tall_Allen

Most guys find multi-month Eligard or Lupron more convenient than monthly Firmagon shots.

3.5 years ago, I switched from 3 month Eligard shots to a 6-month dosage. My remission hasn't skipped a beat. Just throwing it out there, I find it much more convenient. Best of luck.

JohnInTheMiddle profile image
JohnInTheMiddle

I've written several items on Degarelix/Firmagon versus Lupron/Eligard. Most people reduce this to a question of convenience. Here's more information beyond convenience:

healthunlocked.com/advanced...

kainasar profile image
kainasar in reply to JohnInTheMiddle

Thanks.

yardsailor profile image
yardsailor in reply to JohnInTheMiddle

thanks for the info i feel ok with my decision to stick with degarelix I like seeing my doctor once a month and reviewing my blood work

dhccpa profile image
dhccpa

Have you mentioned BAT therapy to him?

yardsailor profile image
yardsailor in reply to dhccpa

I am not castrate resistent yet. but it seems extreme with my bone mets and all . I will look in to it more thanks

Kevinski65 profile image
Kevinski65

You’re welcome

j-o-h-n profile image
j-o-h-n

3 months rowing in your backyard? Geezamacripe.....Must be very OARing going round and round.

Good Luck, Good Health and Good Humor.

j-o-h-n Friday 10/06/2023 5:05 PM DST

yardsailor profile image
yardsailor in reply to j-o-h-n

I just send post cards to every one and they think I still at sea

j-o-h-n profile image
j-o-h-n in reply to yardsailor

Make sure you wet them first............

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That's what I did when I announced to my friends that I had become fully Incontinent.

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Good Luck, Good Health and Good Humor.

j-o-h-n Friday 10/06/2023 8:01 PM DST

MarkBC profile image
MarkBC

I started with monthly Degarelix for the same reason. I switched to 3 month Zoladex after 4 months. I recently switched to 6 month Eligard to make future travel more convenient. All three seemed to be equally effective. My most recent PSA was the lowest it has ever been since diagnosis 5.5 years ago (PSA 0.013). My scans continue to show the bone mets are undetectable.

I found the Degarelix to be the most painful with a large red welt for a few days. Zoladex was a pellet inserted into the belly. It was a little sore but not nearly as bad. The Eligard is a gell. I've only had one so far and it was painless.

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