Plu VI cto: #6 finished under auspices... - Advanced Prostate...

Advanced Prostate Cancer

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Plu VI cto

RunThru profile image
7 Replies

#6 finished under auspices of J Paul Monk OSU yesterday. Definitely aching today. So just listening to Spring spring. Perfect day.

Pre-treatment blood:

PSA 60...yikes, AlPo 190 (ruff)....

Hb 10.3

Felt decent up to about 2 weeks ago. Aches and pains in thighs hips.

PSA was at 35 before last. Started at 15 last September.

Bone/CT scans scheduled in two weeks decide plan. Rechallenge with taxotere suggested.

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RunThru profile image
RunThru
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Tall_Allen profile image
Tall_Allen

Discuss various combinations with Xofigo:

prostatecancer.news/2022/07...

SeosamhM profile image
SeosamhM

Finished #5 - Plu V icto... ;) myself at OSU James yesterday Sorry about the numbers and the upcoming decisions, but, absolutely, it is a beautiful spring day here in Ohio.

I remember back a couple of years ago with everyone clamoring for Lu177 as if it were a miracle. Nope, just another tool, guys. A good tool, but just a tool.

It looks as though my PSMA-avid tumors have shrunk, yes, but my ALP is rising (90 from 67 from a steady 38ish when treatment was working) and Dr. Yang has some suspicion that my cancer is becoming decoupled from PSA expression. This, of course, raises concerns for the appearance of therapy-related neuroendocrine prostate cancer.

But that is for the future. Today, I will take your example and listen once again to life coming back in earnest!

Ramp7 profile image
Ramp7

I completed 6 LuPSMA177 infusions at Dana Farber last year. Initial response very positive but afterward PSA started rising. 8.1 0.19 2.0. Met with Denmeade at Johns Hopkins. Since I had already done Lupron and Zytiga 2 years before with PSA progressing, his opinion was I would be a good candidate for BAT. I did a lot of research, spoke to the MO at Dana Farber, and my regular MO, who cautioned against it. But would help monitor and support me. I decided on BAT and I am indeed a responder. PSA down over 50%. Going into my third cycle. Doing lots of exercise. Big improvement to QOL.

KocoPr profile image
KocoPr in reply to Ramp7

Thats great news on your BAT. Can i adk who is managing it? DF, or Denmeade?

Are you doing their SOC BAT where you cucle every 30 days and staying on ADT while taking Hight T? What T are you taking?

RunThru profile image
RunThru in reply to Ramp7

What's made you a good candidate? Explicitly

Ramp7 profile image
Ramp7 in reply to RunThru

From Dr. Denmeade's point of view having failed Lupron and Zytiga my AR expression would offer a favorable response to a high T environment.

urotoday.com/video-lectures...

Ramp7 profile image
Ramp7

Contact me. Since it is not SOC ,all the Doctors (4) are helping to monitor. I can obtain prescriptions if needed or immediate care. They all seem very pleased with my response.

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