Should I be doing more. : Diagnosed 1... - Advanced Prostate...

Advanced Prostate Cancer

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Should I be doing more.

Letsfish profile image
6 Replies

Diagnosed 11-9-21. PSA 1998, ALK PHOS 750, Gleason 4+5. Lots of mets mostly bone. 11-17-21 started treatment. 3 month Lupron injection followed 2 days later with 4 month Zometa and 1st of 6 cycles of docetaxel. At 2nd chemo PSA 301, ALK P 1730. At completion of chemo 4-8-22 PSA 2.45, ALK P 280. Today I am still on the Lupron / Zometa treatment with PSA .32 (PSA has continued to drop some every blood test), ALK P 81. I do take low dose Morphine for the pain. After reading on the site it seems a more aggressive approach to drop my PSA would have been best. My pain is beginning to increase so it might be to late anyway. My question is, should I be doing more or is what I’m doing good until a scan or blood work shows something different. Thanks.

6 Replies
rsgdmd profile image

What have your follow-up scans showed? Any new mets? Any shrinkage of existing ones? As per PEACE-1 trials, current SOC is triplet therapy for newly diagnosed; but too late for that. Have you asked about 2nd layer of ADT - Zytiga, Xtandi.....

GP24 profile image

You should add either Abiraterone, Enzalutamide, Apalutamide or Darolutamide to lupron. This is the standard of care for you. You could also get your bones radiated to mitigate the pain.

Tall_Allen profile image

I think this would be a good time for Xofigo. Here are some good combinations to discuss with your oncologist:

Letsfish profile image

Thank you for the reply’s. My scans have stayed pretty much the same. Stable and similar to prior exams seems to be a common term in my CT and bone scans. I will discus these options with my doctor. Thanks again.

fmh1 profile image

Sounds like things are going well. I too, had six docetaxel treatments over 18 weeks, 44 months ago, still no detectable PSA. Only additions I had were daily Protectival tablet, three times daily, and the Care Oncology Protocol ( Hope this is helpful!

Boywonder56 profile image

Add second tier.....erleada or such.....

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